Pterosin ZCAS# 34169-69-2 |
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| Cas No. | 34169-69-2 | SDF | Download SDF |
| PubChem ID | 134977 | Appearance | Powder |
| Formula | C15H20O2 | M.Wt | 232.3 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-3H-inden-1-one | ||
| SMILES | CC1=C(C(=C2C(=C1)CC(C2=O)(C)C)C)CCO | ||
| Standard InChIKey | YKQBHPHKXJKKAB-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C15H20O2/c1-9-7-11-8-15(3,4)14(17)13(11)10(2)12(9)5-6-16/h7,16H,5-6,8H2,1-4H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The rhizoma of Cibotium barometz (L.) J.Sm.
| Description | 1. Pterosin Z has smooth muscle relaxant activity, is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M). |
| Targets | Calcium Channel |
Pterosin Z Dilution Calculator
Pterosin Z Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.3048 mL | 21.5239 mL | 43.0478 mL | 86.0956 mL | 107.6195 mL |
| 5 mM | 0.861 mL | 4.3048 mL | 8.6096 mL | 17.2191 mL | 21.5239 mL |
| 10 mM | 0.4305 mL | 2.1524 mL | 4.3048 mL | 8.6096 mL | 10.7619 mL |
| 50 mM | 0.0861 mL | 0.4305 mL | 0.861 mL | 1.7219 mL | 2.1524 mL |
| 100 mM | 0.043 mL | 0.2152 mL | 0.4305 mL | 0.861 mL | 1.0762 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Smooth muscle relaxant activity of pterosin Z and related compounds.[Pubmed:10232079]
Planta Med. 1999 Apr;65(3):271-2.
The natural products Pterosin Z, acetylPterosin Z, originally from the fern Pteridium aquilinum, and their isopterosin analogues have been synthesized and their smooth muscle relaxation activity has been measured. All of the test compounds show activity with Pterosin Z being the most active (EC50 = 1.3 +/- 0.1 x 10(-6) M), exhibiting 100 times the activity reported for the related fern metabolites onitin (EC50 = 1 x 10(-4) M), onotisin (EC50 = 2 x 10(-3) M) and otninoside (EC50 = 7 x 10(-4) M). The smooth muscle relaxant activity of Pterosin Z is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M). These results suggest that smooth muscle relaxant activity is reduced when a phenol group is present in the pterosin nucleus and when one of the dimethyl groups is derivatized.
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