Cyclocalopin ACAS# 486430-94-8 |
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| Cas No. | 486430-94-8 | SDF | Download SDF |
| PubChem ID | 10913461 | Appearance | Powder |
| Formula | C15H20O6 | M.Wt | 296.3 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,3S,3aR,4S,6'S,7aS)-2,6'-dihydroxy-2,2',4-trimethylspiro[3a,4,5,7a-tetrahydrofuro[2,3-c]pyran-3,5'-cyclohex-2-ene]-1',7-dione | ||
| SMILES | CC1COC(=O)C2C1C3(CC=C(C(=O)C3O)C)C(O2)(C)O | ||
| Standard InChIKey | OGOHSCJKRSLFLO-UOMAJYNRSA-N | ||
| Standard InChI | InChI=1S/C15H20O6/c1-7-4-5-15(12(17)10(7)16)9-8(2)6-20-13(18)11(9)21-14(15,3)19/h4,8-9,11-12,17,19H,5-6H2,1-3H3/t8-,9+,11+,12-,14-,15+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The Boletus calopus
| Description | 1. Cyclocalopin A and calopin B show potent free radical-scavenging activity against superoxide, DPPH, and ABTS radicals with IC (50) values of 1.2- 5.4 microg/mL.. |
Cyclocalopin A Dilution Calculator
Cyclocalopin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.375 mL | 16.8748 mL | 33.7496 mL | 67.4992 mL | 84.3739 mL |
| 5 mM | 0.675 mL | 3.375 mL | 6.7499 mL | 13.4998 mL | 16.8748 mL |
| 10 mM | 0.3375 mL | 1.6875 mL | 3.375 mL | 6.7499 mL | 8.4374 mL |
| 50 mM | 0.0675 mL | 0.3375 mL | 0.675 mL | 1.35 mL | 1.6875 mL |
| 100 mM | 0.0337 mL | 0.1687 mL | 0.3375 mL | 0.675 mL | 0.8437 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Free radical-scavenging delta-lactones from Boletus calopus.[Pubmed:17091435]
Planta Med. 2006 Dec;72(15):1431-2.
The methanol extracts from the fruiting body of the mushroom Boletus calopus showed free radical-scavenging activity. Bioactivity-guided fractionation of the methanol extracts led to a new hydroxylated calopin named calopin B, along with the known delta-lactones calopin and Cyclocalopin A. The structure of the new calopin analogue was elucidated by spectroscopic methods. All compounds showed potent free radical-scavenging activity against superoxide, DPPH, and ABTS radicals with IC (50) values of 1.2 - 5.4 microg/mL.
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