D-MentholCAS# 15356-60-2 |
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Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 15356-60-2 | SDF | Download SDF |
| PubChem ID | 439263 | Appearance | Cryst. |
| Formula | C10H20O | M.Wt | 156.27 |
| Type of Compound | Monoterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol | ||
| SMILES | CC1CCC(C(C1)O)C(C)C | ||
| Standard InChIKey | NOOLISFMXDJSKH-UTLUCORTSA-N | ||
| Standard InChI | InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α7-nACh receptors in a noncompetitive manner. Menthol has cooling sensation in the skin, by chemically triggering the cold-sensitive TRPM8 receptors. Menthol has analgesic property, it acts as a noncompetitive antagonist of the 5-HT3 receptor. |
| Targets | Calcium Channel | 5-HT Receptor | AChR |
| In vitro | Effects of d-menthol stress on the growth of and microcystin release by the freshwater cyanobacterium Microcystis aeruginosa FACHB-905.[Pubmed: 25065786 ]Chemosphere. 2014 Oct;113:30-5.The effects of D-Menthol on the growth of Microcystis aeruginosa FACHB-905 and microcystin (MCY) concentration were evaluated by batch culture experiments. |
| Structure Identification | Int J Pharm. 2010 Dec 15;402(1-2):146-52.Different effects of l- and d-menthol on the microstructure of ceramide 5/cholesterol/palmitic acid bilayers.[Pubmed: 20932885]The optical activity of transdermal permeation enhancers is one of the crucial factors for the enhancement of drug permeation via the skin. We investigated the effects of optically active menthols on a lipid bilayer model composed of ceramide 5, cholesterol, and palmitic acid. |
D-Menthol Dilution Calculator
D-Menthol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 6.3992 mL | 31.9959 mL | 63.9918 mL | 127.9836 mL | 159.9795 mL |
| 5 mM | 1.2798 mL | 6.3992 mL | 12.7984 mL | 25.5967 mL | 31.9959 mL |
| 10 mM | 0.6399 mL | 3.1996 mL | 6.3992 mL | 12.7984 mL | 15.998 mL |
| 50 mM | 0.128 mL | 0.6399 mL | 1.2798 mL | 2.5597 mL | 3.1996 mL |
| 100 mM | 0.064 mL | 0.32 mL | 0.6399 mL | 1.2798 mL | 1.5998 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effects of d-menthol stress on the growth of and microcystin release by the freshwater cyanobacterium Microcystis aeruginosa FACHB-905.[Pubmed:25065786]
Chemosphere. 2014 Oct;113:30-5.
The effects of D-Menthol on the growth of Microcystis aeruginosa FACHB-905 and microcystin (MCY) concentration were evaluated by batch culture experiments. The algal biomass and the intracellular and extracellular MCY concentrations were evaluated during 5d incubation. After the D-Menthol exposure, the dry weight of the cells gradually decreased; the decrease in the dry weight after 5d exposure was 29, 12, and 2mgL(-1) when the initial cell densities were 1.4x10(7), 1.2x10(6), and 2.9x10(5)cellmL(-1), respectively. The results indicate that the D-Menthol exposure inhibited the cellular growth, thus also inhibiting the increase of the total MCY concentration. In the presence of D-Menthol, the intracellular MCY was gradually released into the medium after the cell lysis. The extracellular MCY concentration in the medium was significantly higher in the D-Menthol-exposed samples than in the control samples, confirming that D-Menthol cannot decompose the extracellular MCY.
