DHBP dibromide

CAS# 6159-05-3

DHBP dibromide

Catalog No. BCC6811----Order now to get a substantial discount!

Product Name & Size Price Stock
DHBP dibromide: 5mg $12 In Stock
DHBP dibromide: 10mg Please Inquire In Stock
DHBP dibromide: 20mg Please Inquire Please Inquire
DHBP dibromide: 50mg Please Inquire Please Inquire
DHBP dibromide: 100mg Please Inquire Please Inquire
DHBP dibromide: 200mg Please Inquire Please Inquire
DHBP dibromide: 500mg Please Inquire Please Inquire
DHBP dibromide: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of DHBP dibromide

Number of papers citing our products

Chemical structure

DHBP dibromide

3D structure

Chemical Properties of DHBP dibromide

Cas No. 6159-05-3 SDF Download SDF
PubChem ID 80262 Appearance Powder
Formula C24H38Br2N2 M.Wt 514.39
Type of Compound N/A Storage Desiccate at -20°C
Solubility H2O : 100 mg/mL (194.41 mM; Need ultrasonic)
DMSO : ≥ 30 mg/mL (58.32 mM)
*"≥" means soluble, but saturation unknown.
Chemical Name 1-heptyl-4-(1-heptylpyridin-1-ium-4-yl)pyridin-1-ium;dibromide
SMILES CCCCCCC[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCCCCC.[Br-].[Br-]
Standard InChIKey VRXAJMCFEOESJO-UHFFFAOYSA-L
Standard InChI InChI=1S/C24H38N2.2BrH/c1-3-5-7-9-11-17-25-19-13-23(14-20-25)24-15-21-26(22-16-24)18-12-10-8-6-4-2;;/h13-16,19-22H,3-12,17-18H2,1-2H3;2*1H/q+2;;/p-2
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of DHBP dibromide

DescriptionBlocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor.

DHBP dibromide Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

DHBP dibromide Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of DHBP dibromide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9441 mL 9.7203 mL 19.4405 mL 38.881 mL 48.6013 mL
5 mM 0.3888 mL 1.9441 mL 3.8881 mL 7.7762 mL 9.7203 mL
10 mM 0.1944 mL 0.972 mL 1.9441 mL 3.8881 mL 4.8601 mL
50 mM 0.0389 mL 0.1944 mL 0.3888 mL 0.7776 mL 0.972 mL
100 mM 0.0194 mL 0.0972 mL 0.1944 mL 0.3888 mL 0.486 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on DHBP dibromide

Effects of bipyridylium compounds on calcium release from triadic vesicles isolated from rabbit skeletal muscle.[Pubmed:7952884]

Br J Pharmacol. 1994 Aug;112(4):1216-22.

1. The effects of 1,1'-diheptyl-4,4'-bipyridinium dibromide (DHBP), a viologen for electrochromic memory display agent, on calcium release and ryanodine binding were studied with triad-rich sarcoplasmic reticulum (SR) vesicles isolated from rabbit skeletal muscle. 2. DHBP inhibited the calcium release induced by 2 mM caffeine and 2 micrograms ml-1 polylysine with an IC50 value of 5 micrograms ml-1 and 4 micrograms ml-1 respectively. 3. DHBP inhibited [3H]-ryanodine binding in a dose-dependent manner with an IC50 of 2.5 micrograms ml-1 and 90-100% inhibition at 20-30 micrograms ml-1. 4. Calcium uptake by SR was inhibited in the presence of caffeine and this inhibition was antagonized by concomitant addition of DHBP. 5. The effect of DHBP on muscle twitches was studied on the mouse diaphragm. Muscle twitches elicited by direct electrical muscle stimulation and contractions induced by either 10 mM caffeine or 1 microM ryanodine were blocked by pretreatment with DHBP. 6. Data from this study provided evidence that DHBP blocked the calcium release from SR by direct interaction with the calcium release channel, also known as the ryanodine receptor. A possible use of this agent as a specific inhibitor for calcium release and as a muscle relaxant was suggested.

Description

DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.

Keywords:

DHBP dibromide,6159-05-3,Natural Products,Calcium Channel, buy DHBP dibromide , DHBP dibromide supplier , purchase DHBP dibromide , DHBP dibromide cost , DHBP dibromide manufacturer , order DHBP dibromide , high purity DHBP dibromide

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: