DesmethylbellidifolinCAS# 2980-32-7 |
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| Cas No. | 2980-32-7 | SDF | Download SDF |
| PubChem ID | 5281626 | Appearance | Powder |
| Formula | C13H8O6 | M.Wt | 260.2 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1,3,5,8-tetrahydroxyxanthen-9-one | ||
| SMILES | C1=CC(=C2C(=C1O)C(=O)C3=C(C=C(C=C3O2)O)O)O | ||
| Standard InChIKey | MPXAWSABMVLIBU-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C13H8O6/c14-5-3-8(17)10-9(4-5)19-13-7(16)2-1-6(15)11(13)12(10)18/h1-4,14-17H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Gentiana bellidifolia
| Description | 1. Desmethylbellidifolin shows stronger antioxidative properties than those of butylated hydroxytoluene (BHT) and α-tocopherol. 2. Desmethylbellidifolin exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus. 3. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method. |
| Targets | Antifection |
Desmethylbellidifolin Dilution Calculator
Desmethylbellidifolin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.8432 mL | 19.216 mL | 38.432 mL | 76.864 mL | 96.0799 mL |
| 5 mM | 0.7686 mL | 3.8432 mL | 7.6864 mL | 15.3728 mL | 19.216 mL |
| 10 mM | 0.3843 mL | 1.9216 mL | 3.8432 mL | 7.6864 mL | 9.608 mL |
| 50 mM | 0.0769 mL | 0.3843 mL | 0.7686 mL | 1.5373 mL | 1.9216 mL |
| 100 mM | 0.0384 mL | 0.1922 mL | 0.3843 mL | 0.7686 mL | 0.9608 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Mutagenicities of xanthone derivatives in Salmonella typhimurium TA100, TA98, TA97, and TA2637.[Pubmed:3889613]
Mutat Res. 1985 Jun-Jul;150(1-2):141-6.
The mutagenicities of naturally occurring xanthones were tested in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method. Xanthydrol, gentisein, gentisin, isogentisin, 1-hydroxy-3,7-dimethoxyxanthone, 1,3,7-trimethoxyxanthone, Desmethylbellidifolin, bellidifolin and dimethylbellidifolin were mutagenic, but unsubstituted xanthone was not mutagenic to TA100, TA98, TA97 and TA2637 with or without a metabolic activation system. The beta-O-glucosides, norswertianolin and swertianolin, were only mutagenic when a metabolic activation system containing beta-glucosidase was used, and the C-glucoside mangiferin was not mutagenic even with this system.
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity.
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