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Isobellidifolin

CAS# 552-00-1

Isobellidifolin

Catalog No. BCX1286----Order now to get a substantial discount!

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Chemical structure

Isobellidifolin

3D structure

Chemical Properties of Isobellidifolin

Cas No. 552-00-1 SDF Download SDF
PubChem ID 5322042.0 Appearance Powder
Formula C14H10O6 M.Wt 274.23
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1,3,8-trihydroxy-5-methoxyxanthen-9-one
SMILES COC1=C2C(=C(C=C1)O)C(=O)C3=C(C=C(C=C3O2)O)O
Standard InChIKey QNJCJDZKEAVOBJ-UHFFFAOYSA-N
Standard InChI InChI=1S/C14H10O6/c1-19-9-3-2-7(16)12-13(18)11-8(17)4-6(15)5-10(11)20-14(9)12/h2-5,15-17H,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Isobellidifolin Dilution Calculator

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Isobellidifolin Molarity Calculator

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Preparing Stock Solutions of Isobellidifolin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6466 mL 18.2329 mL 36.4657 mL 72.9315 mL 91.1644 mL
5 mM 0.7293 mL 3.6466 mL 7.2931 mL 14.5863 mL 18.2329 mL
10 mM 0.3647 mL 1.8233 mL 3.6466 mL 7.2931 mL 9.1164 mL
50 mM 0.0729 mL 0.3647 mL 0.7293 mL 1.4586 mL 1.8233 mL
100 mM 0.0365 mL 0.1823 mL 0.3647 mL 0.7293 mL 0.9116 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Isobellidifolin

Chemical Composition, Antioxidant and Anticholinesterase Activities of Gentianella azurea from Russian Federation.[Pubmed:30549824]

Nat Prod Commun. 2017 Jan;12(1):55-56.

Phytochemical study of Gentianella azurea (Bunge) Holub (Gentianaceae) collected in Buryatia Republic (Russian Federation) resulted in the isolation of twenty-one compounds including bellidifolin, bellidin, Isobellidifolin, norswertianolin, Isobellidifolin-8-O-beta-D-glucopyranoside, orientin, cynaroside, .cosmosiin, apigenin, 4'-O-caffeoylswertiamarin, swertiamarin-6'-O-beta-D-glucopyranoside and sweroside, firstly detected in this species. The extracts and individual compounds were shown to possess antioxidant and anticholinesterase potential.

Antimicrobial and antioxidant activities of Gentianella multicaulis collected on the Andean Slopes of San Juan Province, Argentina.[Pubmed:22486039]

Z Naturforsch C J Biosci. 2012 Jan-Feb;67(1-2):29-38.

The infusion of the aerial parts of Gentianella multicaulis (Gillies ex Griseb.) Fabris (Gentianaceae), locally known as 'nencia', is used in San Juan Province, Argentina, as stomachic and as a bitter tonic against digestive and liver problems. The bioassay-guided isolation of G. multicaulis extracts and structural elucidation of the main compounds responsible for the antifungal and free radical scavenging activities were performed. The extracts had strong free radical scavenging effects in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (45-93% at 10 microg/mL) and ferric-reducing antioxidant power (FRAP) assay at 200 microg/mL. Demethylbellidifolin (4) had high antioxidant activity in the DPPH and FRAP assay. The dermatophytes Microsporum gypseum, Trichophyton mentagrophytes, and T. rubrum were moderately inhibited by the different extracts (MIC values of 125-250 microg/mL). Demethylbellidifolin (4), bellidifolin (5), and Isobellidifolin (6) showed an antifungal effect (MIC values of 50 microg/mL), while swerchirin (3) was less active with a MIC value of 100 microg/mL. In addition, oleanolic acid (1) and ursolic acid (2) were also isolated. These findings demonstrate that Gentianella multicaulis collected in the mountains of the Province of San Juan, Argentina, is an important source of compounds with antifungal and antioxidant activities.

Activity-guided isolation of antioxidant xanthones from Swertia chirayita (Roxb.) H. Karsten (Gentianaceae).[Pubmed:21985644]

Nat Prod Res. 2012;26(18):1682-6.

An activity-guided isolation and purification process was used to identify the DPPH (l,l-diphenyl-2-picrylhydrazyl) radical-scavenging components of Swertia chirayita. A dry, whole plant of S. chirayita was extracted with different solvents and tested for its DPPH radical-scavenging activity. The acetone : water (8 : 2) extract showed the highest total phenolic content (TPC) and DPPH radical-scavenging activity, which was column chromatographed to obtain decussatin, swertianin, bellidifolin, Isobellidifolin, amarogentin, swertianolin and mangiferin as active components. Good correlation was observed between TPC and DPPH scavenging activity among the extracts. The unique structure of xanthones, including the catecholic moiety and the completely conjugated system, enables them to be promising antioxidants.

Two new xanthone diglycosides from Swertia longifolia Boiss.[Pubmed:17127518]

Nat Prod Res. 2006 Nov;20(13):1251-7.

From aerial parts of Swertia longifolia Boiss., which grows in the north of Iran, five xanthones, two of which in diglycosidic form, were isolated. The structures were confirmed by means of their spectral data as Isobellidifolin, bellidin, gentisein, 1,5-dihydroxy-3-methoxy-6-O-primeverosyl xanthone, and 8-hydroxy-3,5-dimethoxy-1-O-primeverosyl xanthone, the latter two of which were new derivatives in the plant kingdom.

Xanthones from Swertia punctata.[Pubmed:12377236]

Phytochemistry. 2002 Oct;61(4):415-20.

Isolation of 1-O-primeverosyl-3,8-dihydroxy-5-methoxyxanthone and 1-O-gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone, along with five known xanthones, Isobellidifolin, methylbellidifolin, isoswertianin, methylswertianin and norswertianin-1-O-beta-D-glucoside, from the roots of Swertia punctata is reported. In the aerial parts four xanthones, bellidifolin, methylbellidifolin, swertianolin and mangiferin, and flavone-C-glucoside, isoorientin were identified. The chemotaxonomic and pharmacological significance of these results is discussed.

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