Epimedonin B

CAS# 1616061-69-8

Epimedonin B

Catalog No. BCN7889----Order now to get a substantial discount!

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Quality Control of Epimedonin B

Number of papers citing our products

Chemical structure

Epimedonin B

3D structure

Chemical Properties of Epimedonin B

Cas No. 1616061-69-8 SDF Download SDF
PubChem ID 118707717 Appearance Powder
Formula C20H16O6 M.Wt 352.34
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5-hydroxy-2-(4-hydroxyphenoxy)-8,8-dimethylpyrano[2,3-h]chromen-4-one
SMILES CC1(C=CC2=C3C(=C(C=C2O1)O)C(=O)C=C(O3)OC4=CC=C(C=C4)O)C
Standard InChIKey XWLMKXLXTCJNHF-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H16O6/c1-20(2)8-7-13-16(26-20)9-14(22)18-15(23)10-17(25-19(13)18)24-12-5-3-11(21)4-6-12/h3-10,21-22H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Epimedonin B

The herbs of Epimedium koreanum

Biological Activity of Epimedonin B

DescriptionEpimedonin B is a natural product from Epimedium koreanum.

Protocol of Epimedonin B

Structure Identification
J Nat Prod. 2018 Jan 26;81(1):16-21.

Prenylated 2-Phenoxychromones and Flavonoids from Epimedium brevicornum and Revised Structures of Epimedonins A and B.[Pubmed: 29338226 ]


METHODS AND RESULTS:
Six hitherto unknown prenylated 2-phenoxychromones, epimedonin G (1), 7-O-methylepimedonin G (2), and epimedonins H-K (3-6), and two new prenylflavonoids, epimedonin L (7) and 3″-O-desmethylspinorhamnoside (8), were isolated from an ethanol extract of the aerial parts of Epimedium brevicornum. Their structures were established on the basis of spectroscopic data interpretation.
CONCLUSIONS:
Compound 7 exhibited cytotoxic activity when evaluated against four human cancer cell lines (HL-60, A-549, MCF-7, and SW-480), with IC50 values of <10 μM. In addition, the structures of epimedonin A and Epimedonin B (9a, 10a), recently isolated from E. koreanum, were corrected by reanalysis of the published NMR data.

Epimedonin B Dilution Calculator

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Epimedonin B Molarity Calculator

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Preparing Stock Solutions of Epimedonin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8382 mL 14.1908 mL 28.3817 mL 56.7634 mL 70.9542 mL
5 mM 0.5676 mL 2.8382 mL 5.6763 mL 11.3527 mL 14.1908 mL
10 mM 0.2838 mL 1.4191 mL 2.8382 mL 5.6763 mL 7.0954 mL
50 mM 0.0568 mL 0.2838 mL 0.5676 mL 1.1353 mL 1.4191 mL
100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5676 mL 0.7095 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Epimedonin B

Prenylated 2-Phenoxychromones and Flavonoids from Epimedium brevicornum and Revised Structures of Epimedonins A and B.[Pubmed:29338226]

J Nat Prod. 2018 Jan 26;81(1):16-21.

Six hitherto unknown prenylated 2-phenoxychromones, epimedonin G (1), 7-O-methylepimedonin G (2), and epimedonins H-K (3-6), and two new prenylflavonoids, epimedonin L (7) and 3''-O-desmethylspinorhamnoside (8), were isolated from an ethanol extract of the aerial parts of Epimedium brevicornum. Their structures were established on the basis of spectroscopic data interpretation. Compound 7 exhibited cytotoxic activity when evaluated against four human cancer cell lines (HL-60, A-549, MCF-7, and SW-480), with IC50 values of <10 muM. In addition, the structures of epimedonins A and B (9a, 10a), recently isolated from E. koreanum, were corrected by reanalysis of the published NMR data.

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