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H-D-Pen-OH

CAS# 52-67-5

H-D-Pen-OH

2D Structure

Catalog No. BCC3307----Order now to get a substantial discount!

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H-D-Pen-OH: 5mg	$12	In Stock
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Quality Control of H-D-Pen-OH

Quality Control & MSDS

Purity: >98%

3D structure

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Chemical Properties of H-D-Pen-OH

Cas No.	52-67-5	SDF	Download SDF
PubChem ID	5852	Appearance	Powder
Formula	C5H11NO2S	M.Wt	149.2
Type of Compound	N/A	Storage	Desiccate at -20°C
Synonyms	D-Penicillamine; Penicillamine; 52-67-5; Cuprimine; D-(-)-Penicillamine
Solubility	H2O : 50 mg/mL (335.10 mM; Need ultrasonic) DMSO : 1.43 mg/mL (9.58 mM; Need ultrasonic)
Chemical Name	(2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
SMILES	CC(C)(C(C(=O)O)N)S
Standard InChIKey	VVNCNSJFMMFHPL-VKHMYHEASA-N
Standard InChI	InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging	1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment.
Shipping Condition	Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of H-D-Pen-OH

Description

Penicillamine is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. Target: Others Penicillamine(Cuprimine, Depen) is used as an antirheumatic and as a chelating agent in Wilson's disease and is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. From in vitro studies which indicate that one atom of copper combines with two molecules of penicillamine. Penicillamine also reduces excess cystine excretion in cystinuria. The mechanism of action of penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, penicillamine in vitro depresses T-cell activity but not B-cell activity [1-3].

References:
[1]. Peisach, J. and W.E. Blumberg, A mechanism for the action of penicillamine in the treatment of Wilson's disease. Mol Pharmacol, 1969. 5(2): p. 200-9. [2]. Jaffe, I.A., K. Altman, and P. Merryman, The Antipyridoxine Effect of Penicillamine in Man. J Clin Invest, 1964. 43: p. 1869-73. [3]. Camp, A.V., Penicillamine in the treatment of rheumatoid arthritis. Proc R Soc Med, 1977. 70(2): p. 67-9.

H-D-Pen-OH Dilution Calculator

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Preparing Stock Solutions of H-D-Pen-OH

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	6.7024 mL	33.5121 mL	67.0241 mL	134.0483 mL	167.5603 mL
5 mM	1.3405 mL	6.7024 mL	13.4048 mL	26.8097 mL	33.5121 mL
10 mM	0.6702 mL	3.3512 mL	6.7024 mL	13.4048 mL	16.756 mL
50 mM	0.134 mL	0.6702 mL	1.3405 mL	2.681 mL	3.3512 mL
100 mM	0.067 mL	0.3351 mL	0.6702 mL	1.3405 mL	1.6756 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on H-D-Pen-OH

H-D-Pen-OH

Description

Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics.

Keywords:

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H-D-Pen-OH

Catalog No. BCC3307----Order now to get a substantial discount!

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Quality Control of H-D-Pen-OH

Quality Control & MSDS

3D structure

Package In Stock

Number of papers citing our products

Chemical Properties of H-D-Pen-OH

Biological Activity of H-D-Pen-OH

H-D-Pen-OH Dilution Calculator

H-D-Pen-OH Molarity Calculator

Preparing Stock Solutions of H-D-Pen-OH

Organizitions Citing Our Products recently

Background on H-D-Pen-OH

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