6-MethoxyluteolinCAS# 520-11-6 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 520-11-6 | SDF | Download SDF |
| PubChem ID | 5317284 | Appearance | Yellow powder |
| Formula | C16H12O7 | M.Wt | 316.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Synonyms | Eupafolin; 6-Methoxyluteolin; 3',4',5,7-Tetrahydroxy 6-methoxyflavone | ||
| Solubility | Soluble in methanol; slightly soluble in water | ||
| Chemical Name | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one | ||
| SMILES | COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC(=C(C=C3)O)O)O | ||
| Standard InChIKey | FHHSEFRSDKWJKJ-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
1 Arnica sp. 2 Artemisia sp. 3 Baccharis sp. 4 Centaurea sp. 5 Cirsium sp. 6 Eupatorium sp. 7 Inula sp. 8 Lippia sp. 9 Salvia sp. 10 Scutellaria sp. 11 Tanacetum sp.
| Description | 1. 6-Methoxyluteolin has antioxidant activity. 2. 6-Methoxyluteolin is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
| Targets | Calcium Channel | Histamine Receptor |
6-Methoxyluteolin Dilution Calculator
6-Methoxyluteolin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1616 mL | 15.8078 mL | 31.6156 mL | 63.2311 mL | 79.0389 mL |
| 5 mM | 0.6323 mL | 3.1616 mL | 6.3231 mL | 12.6462 mL | 15.8078 mL |
| 10 mM | 0.3162 mL | 1.5808 mL | 3.1616 mL | 6.3231 mL | 7.9039 mL |
| 50 mM | 0.0632 mL | 0.3162 mL | 0.6323 mL | 1.2646 mL | 1.5808 mL |
| 100 mM | 0.0316 mL | 0.1581 mL | 0.3162 mL | 0.6323 mL | 0.7904 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- H-Cys-OH
Catalog No.:BCC2902
CAS No.:52-90-4
- Haloperidol
Catalog No.:BCC4909
CAS No.:52-86-8
- Lynestrenol
Catalog No.:BCC9014
CAS No.:52-76-6
- H-D-Pen-OH
Catalog No.:BCC3307
CAS No.:52-67-5
- Morphine hydrochloride
Catalog No.:BCC6368
CAS No.:52-26-6
- Thio-TEPA
Catalog No.:BCC5354
CAS No.:52-24-4
- Prednisolone Acetate
Catalog No.:BCC4831
CAS No.:52-21-1
- Spironolactone
Catalog No.:BCC4366
CAS No.:52-01-7
- Dehydroespeletone
Catalog No.:BCN5652
CAS No.:51995-99-4
- Schaftoside
Catalog No.:BCN2343
CAS No.:51938-32-0
- 5-Aminoindole
Catalog No.:BCC8735
CAS No.:5192-03-0
- TNP
Catalog No.:BCC7822
CAS No.:519178-28-0
New Products
- Pectolinarigenin
Catalog No.:BCN5813
CAS No.:520-12-7
- Kaempferol
Catalog No.:BCN5653
CAS No.:520-18-3
- Hesperidin
Catalog No.:BCN5654
CAS No.:520-26-3
- Diosimin
Catalog No.:BCN4993
CAS No.:520-27-4
- Tectochrysin
Catalog No.:BCN5655
CAS No.:520-28-5
- Tricin
Catalog No.:BCN5656
CAS No.:520-32-1
- Hesperetin
Catalog No.:BCN5657
CAS No.:520-33-2
- Diosmetin
Catalog No.:BCN2356
CAS No.:520-34-3
- Apigenin
Catalog No.:BCN5658
CAS No.:520-36-5
- Asebogenin
Catalog No.:BCN7232
CAS No.:520-42-3
- Psilocin
Catalog No.:BCC6168
CAS No.:520-53-6
- Spectabiline
Catalog No.:BCN2098
CAS No.:520-55-8
6-Methoxyluteolin from Chrysanthemum zawadskii var. latilobum suppresses histamine release and calcium influx via down-regulation of FcepsilonRI alpha chain expression.[Pubmed:22561855]
J Microbiol Biotechnol. 2012 May;22(5):622-7.
Mast cells and basophils are important effector cells in immunoglobulin-E (IgE)-mediated allergic reactions. Using the human basophilic KU812F cells, we assessed the inhibitory effects of 6-Methoxyluteolin, isolated from Chrysanthemum zawadskii, in the FcepsilonRI-mediated allergic reaction. We determined that 6-Methoxyluteolin inhibited anti-FcepsilonRI alpha chain antibody (CRA-1)-induced histamine release, as well as elevation of intracellular calcium concentration [Ca2+]i in a dose-dependent manner. Moreover, the inhibitory effects of 6-Methoxyluteolin on the cell surface expression and the mRNA level of the FcepsilonRI alpha chain were determined by flow cytometric analysis and reverse transcription-polymerase chain reaction (RTPCR), respectively. Therefore, these results show that 6- methoxyluteolin is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcepsilonRI alpha chain.
Nepetin (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activities. Nepetin inhibits IL-6, IL-8 and MCP-1 secretion with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively in ARPE-19 cells.
6-Methoxyluteolin,520-11-6,Eupafolin; 6-Methoxyluteolin; 3',4',5,7-Tetrahydroxy 6-methoxyflavone,Natural Products, buy 6-Methoxyluteolin , 6-Methoxyluteolin supplier , purchase 6-Methoxyluteolin , 6-Methoxyluteolin cost , 6-Methoxyluteolin manufacturer , order 6-Methoxyluteolin , high purity 6-Methoxyluteolin
