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Nepetin-7-glucoside

CAS# 569-90-4

Nepetin-7-glucoside

2D Structure

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3D structure

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Nepetin-7-glucoside

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Chemical Properties of Nepetin-7-glucoside

Cas No. 569-90-4 SDF Download SDF
PubChem ID 120742 Appearance Yellow powder
Formula C22H22O12 M.Wt 478.40
Type of Compound Flavonoids Storage Desiccate at -20°C
Synonyms Eupafolin 7-O-β-glucoside; 6-Methoxyluteolin 7-glucoside; Nepetrin; Nepitrin; 3',4',5,7-Tetrahydroxy 6-methoxyflavone 7-β-D-glucoside
Solubility Soluble in methan
Chemical Name 2-(3,4-dihydroxyphenyl)-5-hydroxy-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
SMILES COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC(=C(C=C3)O)O)OC4C(C(C(C(O4)CO)O)O)O
Standard InChIKey DMXHXBGUNHLMQO-IWLDQSELSA-N
Standard InChI InChI=1S/C22H22O12/c1-31-21-14(33-22-20(30)19(29)17(27)15(7-23)34-22)6-13-16(18(21)28)11(26)5-12(32-13)8-2-3-9(24)10(25)4-8/h2-6,15,17,19-20,22-25,27-30H,7H2,1H3/t15-,17-,19+,20-,22-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Nepetin-7-glucoside

1 Inula sp. 2 Plantago sp. 3 Rosmarinus sp. 4 Salvia sp.

Biological Activity of Nepetin-7-glucoside

DescriptionNepetin-7-glucoside has antioxidant activity in human HL60 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation.
TargetsP450 (e.g. CYP17)

Protocol of Nepetin-7-glucoside

Structure Identification
J Pharm Biomed Anal. 2008 Sep 10;48(1):100-4.

Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatography.[Pubmed: 18678457]


METHODS AND RESULTS:
To control the quality of Salvia plebeia R.Br., a simple and reliable method of high-performance liquid chromatography coupled with photodiode array detector (HPLC-DAD) was developed both for fingerprint analysis and quantitative determination of seven bioactive compounds, namely caffeic acid, luteolin-7-glucoside, Nepetin-7-glucoside, homoplantaginin, luteolin, nepetin and hispidulin. In fingerprint analysis, twelve peaks were selected as characteristic peaks. In quantitative analysis, seven compounds showed good regression (R2>0.9995) within test ranges and the recovery of the method was in the range of 91.7-103.2%. The content ranges (mg/g) of seven compounds in the collected samples of S. plebeia were 0.80-1.67 (hispidulin), 2.18-5.75 (homoplantaginin), 0.52-1.22 (nepetin), 1.56-3.48 (Nepetin-7-glucoside), 0.12-0.24 (luteolin), 0.97-2.22 (luteolin-7-glucoside) and 0.21-0.44 (caffeic acid), respectively.
CONCLUSIONS:
From the results obtained, the content of homoplantaginin was the highest. In addition, luteolin and luteolin-7-glucoside were isolated for the first time from S. plebeia.

Nepetin-7-glucoside Dilution Calculator

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Preparing Stock Solutions of Nepetin-7-glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0903 mL 10.4515 mL 20.903 mL 41.806 mL 52.2575 mL
5 mM 0.4181 mL 2.0903 mL 4.1806 mL 8.3612 mL 10.4515 mL
10 mM 0.209 mL 1.0452 mL 2.0903 mL 4.1806 mL 5.2258 mL
50 mM 0.0418 mL 0.209 mL 0.4181 mL 0.8361 mL 1.0452 mL
100 mM 0.0209 mL 0.1045 mL 0.209 mL 0.4181 mL 0.5226 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Nepetin-7-glucoside

Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatography.[Pubmed:18678457]

J Pharm Biomed Anal. 2008 Sep 10;48(1):100-4.

To control the quality of Salvia plebeia R.Br., a simple and reliable method of high-performance liquid chromatography coupled with photodiode array detector (HPLC-DAD) was developed both for fingerprint analysis and quantitative determination of seven bioactive compounds, namely caffeic acid, luteolin-7-glucoside, Nepetin-7-glucoside, homoplantaginin, luteolin, nepetin and hispidulin. In fingerprint analysis, twelve peaks were selected as characteristic peaks. In quantitative analysis, seven compounds showed good regression (R2>0.9995) within test ranges and the recovery of the method was in the range of 91.7-103.2%. The content ranges (mg/g) of seven compounds in the collected samples of S. plebeia were 0.80-1.67 (hispidulin), 2.18-5.75 (homoplantaginin), 0.52-1.22 (nepetin), 1.56-3.48 (Nepetin-7-glucoside), 0.12-0.24 (luteolin), 0.97-2.22 (luteolin-7-glucoside) and 0.21-0.44 (caffeic acid), respectively. From the results obtained, the content of homoplantaginin was the highest. In addition, luteolin and luteolin-7-glucoside were isolated for the first time from S. plebeia.

Description

Nepitrin, isolated from Scrophularia striata, possess significant anti-inflammatory and anti-arthritic activity.

Keywords:

Nepetin-7-glucoside,569-90-4,Eupafolin 7-O-β-glucoside; 6-Methoxyluteolin 7-glucoside; Nepetrin; Nepitrin; 3',4',5,7-Tetrahydroxy 6-methoxyflavone 7-β-D-glucoside,Natural Products, buy Nepetin-7-glucoside , Nepetin-7-glucoside supplier , purchase Nepetin-7-glucoside , Nepetin-7-glucoside cost , Nepetin-7-glucoside manufacturer , order Nepetin-7-glucoside , high purity Nepetin-7-glucoside

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