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Isomaculosidine

CAS# 518-96-7

Isomaculosidine

2D Structure

Catalog No. BCN7069----Order now to get a substantial discount!

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Quality Control of Isomaculosidine

3D structure

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Isomaculosidine

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Chemical Properties of Isomaculosidine

Cas No. 518-96-7 SDF Download SDF
PubChem ID 3083609 Appearance Powder
Formula C14H13NO4 M.Wt 259.26
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6,8-dimethoxy-9-methylfuro[2,3-b]quinolin-4-one
SMILES CN1C2=C(C=C(C=C2C(=O)C3=C1OC=C3)OC)OC
Standard InChIKey FXHBKLQQNAGNJN-UHFFFAOYSA-N
Standard InChI InChI=1S/C14H13NO4/c1-15-12-10(6-8(17-2)7-11(12)18-3)13(16)9-4-5-19-14(9)15/h4-7H,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Isomaculosidine

The root barks of Dictamnus dasycarpus.

Biological Activity of Isomaculosidine

Description1. Isomaculosidine can significantly inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells.
TargetsNO

Isomaculosidine Dilution Calculator

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Isomaculosidine Molarity Calculator

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Preparing Stock Solutions of Isomaculosidine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8571 mL 19.2857 mL 38.5713 mL 77.1426 mL 96.4283 mL
5 mM 0.7714 mL 3.8571 mL 7.7143 mL 15.4285 mL 19.2857 mL
10 mM 0.3857 mL 1.9286 mL 3.8571 mL 7.7143 mL 9.6428 mL
50 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.5429 mL 1.9286 mL
100 mM 0.0386 mL 0.1929 mL 0.3857 mL 0.7714 mL 0.9643 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Isomaculosidine

Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells.[Pubmed:21827366]

J Enzyme Inhib Med Chem. 2012 Aug;27(4):490-4.

The methanolic extract of Dictamnus dasycarpus root barks afforded one new glycosidic quinoline alkaloid, 3-[1beta-hydroxy-2-(beta-D-glucopyranosyloxy)-ethyl)-4-methoxy-2(1H)-quinolinone (1), together with nine known compounds, preskimmianine (2), 8-methoxy-N-methylflindersine (3), dictamine (4), gamma-fagarine (5), halopine (6), skimmianine (7), dictangustine-A (8), iso-gamma-fagarine (9), Isomaculosidine (10). The isolated alkaloids significantly inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells. Among them, compounds 3 and 7 showed the most potent inhibitory activities on LPS-induced NO production.

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