Rengynic acid

CAS# 517883-38-4

Rengynic acid

2D Structure

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Rengynic acid

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Chemical Properties of Rengynic acid

Cas No. 517883-38-4 SDF Download SDF
PubChem ID 54033324 Appearance Powder
Formula C8H14O4 M.Wt 174.2
Type of Compound Miscellaneous Storage Desiccate at -20°C
Synonyms Epirengynic acid;1310146-00-9
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-(1,4-dihydroxycyclohexyl)acetic acid
SMILES C1CC(CCC1O)(CC(=O)O)O
Standard InChIKey LHDVONJKFJRQTI-UHFFFAOYSA-N
Standard InChI InChI=1S/C8H14O4/c9-6-1-3-8(12,4-2-6)5-7(10)11/h6,9,12H,1-5H2,(H,10,11)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rengynic acid

The fruits of Forsythia suspensa

Biological Activity of Rengynic acid

Description1. Rengynic acid has potent antiviral effect on RSV for the first time in vitro.
TargetsAntifection

Rengynic acid Dilution Calculator

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Rengynic acid Molarity Calculator

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Preparing Stock Solutions of Rengynic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.7405 mL 28.7026 mL 57.4053 mL 114.8106 mL 143.5132 mL
5 mM 1.1481 mL 5.7405 mL 11.4811 mL 22.9621 mL 28.7026 mL
10 mM 0.5741 mL 2.8703 mL 5.7405 mL 11.4811 mL 14.3513 mL
50 mM 0.1148 mL 0.5741 mL 1.1481 mL 2.2962 mL 2.8703 mL
100 mM 0.0574 mL 0.287 mL 0.5741 mL 1.1481 mL 1.4351 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rengynic acid

A new compound from Forsythia suspensa (Thunb.) Vahl with antiviral effect on RSV.[Pubmed:15277088]

J Herb Pharmacother. 2002;2(3):35-40.

A new compound, 2-(1,4-dihydroxy cyclohexanyl )-acetic acid isolated from the seeds of Forsythia suspensa (Thunb.) Vahl, has been assessed for potent antiviral effect on RSV for the first time in vitro by cell morphology methods. Its structure was elucidated on the basis of spectroscopic evidence (IR, MS, 1H-NMR, 13C-NMR). We have trivially named it Rengynic acid.

Two new glycosides from the fruits of Forsythia suspense.[Pubmed:24506327]

J Asian Nat Prod Res. 2014;16(4):376-82.

Two new glycosides suspensaside C (1) and 2,3,5,6-tetrahydro-jacaranone-4-O-beta-D-glucopyranoside (2), together with four known compounds suspensaside A (3), Rengynic acid-1'-O-beta-D-glucopyranoside (4), forsythoside A (5), and Rengynic acid (6), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. The structures of 1 and 2 were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HR-ESI-MS. All isolates were tested for their cytotoxicities against five human cancer cell lines (A549, Colo-205, Hep-3B, HL60, and KB). Compound 3 exhibited cytotoxicity against HL-60, Hep-3B, and A549 cancer cell lines.

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