Kushenol XCAS# 254886-77-6 |
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| Cas No. | 254886-77-6 | SDF | Download SDF |
| PubChem ID | 10599228 | Appearance | Cryst. |
| Formula | C25H28O7 | M.Wt | 440.5 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)-2,3-dihydrochromen-4-one | ||
| SMILES | CC(=CCC(CC1=C(C=C(C2=C1OC(C(C2=O)O)C3=C(C=C(C=C3)O)O)O)O)C(=C)C)C | ||
| Standard InChIKey | ZJRPDIPXWGIHRB-SBCNVUAESA-N | ||
| Standard InChI | InChI=1S/C25H28O7/c1-12(2)5-6-14(13(3)4)9-17-19(28)11-20(29)21-22(30)23(31)25(32-24(17)21)16-8-7-15(26)10-18(16)27/h5,7-8,10-11,14,23,25-29,31H,3,6,9H2,1-2,4H3/t14?,23-,25+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Sophora flavescens Ait.
| Description | 1. Kushenol X exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). |
Kushenol X Dilution Calculator
Kushenol X Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2701 mL | 11.3507 mL | 22.7015 mL | 45.403 mL | 56.7537 mL |
| 5 mM | 0.454 mL | 2.2701 mL | 4.5403 mL | 9.0806 mL | 11.3507 mL |
| 10 mM | 0.227 mL | 1.1351 mL | 2.2701 mL | 4.5403 mL | 5.6754 mL |
| 50 mM | 0.0454 mL | 0.227 mL | 0.454 mL | 0.9081 mL | 1.1351 mL |
| 100 mM | 0.0227 mL | 0.1135 mL | 0.227 mL | 0.454 mL | 0.5675 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Binding of flavonoids from Sophora flavescens to the rat uterine estrogen receptor.[Pubmed:16320211]
Planta Med. 2005 Nov;71(11):1065-8.
Prenylflavonoids and lavandulylflavonoids were isolated from the roots of Sophora flavescens Aiton (Fabaceae). The ability of 8-prenylkaempferol (1), Kushenol X (2), norkurarinone (3), leachianone A (4), kushenol C (5), maackiain (6) and a root-extract of S. flavescens to displace 17beta-estradiol (E2) from rat uterine estrogen receptor (ER) was determined. Relative binding affinities (RBA) of prenylated flavonoids were weak with RBA values between 0.004 and 0.072. A lavandulyl or prenyl group at the position 8 enhanced binding to rat uterine ER.
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