Kushenol X

CAS# 254886-77-6

Kushenol X

Catalog No. BCN3350----Order now to get a substantial discount!

Product Name & Size Price Stock
Kushenol X: 5mg $989 In Stock
Kushenol X: 10mg Please Inquire In Stock
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Quality Control of Kushenol X

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Chemical structure

Kushenol X

3D structure

Chemical Properties of Kushenol X

Cas No. 254886-77-6 SDF Download SDF
PubChem ID 10599228 Appearance Cryst.
Formula C25H28O7 M.Wt 440.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)-2,3-dihydrochromen-4-one
SMILES CC(=CCC(CC1=C(C=C(C2=C1OC(C(C2=O)O)C3=C(C=C(C=C3)O)O)O)O)C(=C)C)C
Standard InChIKey ZJRPDIPXWGIHRB-SBCNVUAESA-N
Standard InChI InChI=1S/C25H28O7/c1-12(2)5-6-14(13(3)4)9-17-19(28)11-20(29)21-22(30)23(31)25(32-24(17)21)16-8-7-15(26)10-18(16)27/h5,7-8,10-11,14,23,25-29,31H,3,6,9H2,1-2,4H3/t14?,23-,25+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Kushenol X

The roots of Sophora flavescens Ait.

Biological Activity of Kushenol X

Description1. Kushenol X exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).

Kushenol X Dilution Calculator

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Kushenol X Molarity Calculator

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Preparing Stock Solutions of Kushenol X

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2701 mL 11.3507 mL 22.7015 mL 45.403 mL 56.7537 mL
5 mM 0.454 mL 2.2701 mL 4.5403 mL 9.0806 mL 11.3507 mL
10 mM 0.227 mL 1.1351 mL 2.2701 mL 4.5403 mL 5.6754 mL
50 mM 0.0454 mL 0.227 mL 0.454 mL 0.9081 mL 1.1351 mL
100 mM 0.0227 mL 0.1135 mL 0.227 mL 0.454 mL 0.5675 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Kushenol X

Binding of flavonoids from Sophora flavescens to the rat uterine estrogen receptor.[Pubmed:16320211]

Planta Med. 2005 Nov;71(11):1065-8.

Prenylflavonoids and lavandulylflavonoids were isolated from the roots of Sophora flavescens Aiton (Fabaceae). The ability of 8-prenylkaempferol (1), Kushenol X (2), norkurarinone (3), leachianone A (4), kushenol C (5), maackiain (6) and a root-extract of S. flavescens to displace 17beta-estradiol (E2) from rat uterine estrogen receptor (ER) was determined. Relative binding affinities (RBA) of prenylated flavonoids were weak with RBA values between 0.004 and 0.072. A lavandulyl or prenyl group at the position 8 enhanced binding to rat uterine ER.

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