Medicagol

CAS# 1983-72-8

Medicagol

2D Structure

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Quality Control of Medicagol

3D structure

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Medicagol

Number of papers citing our products

Chemical Properties of Medicagol

Cas No. 1983-72-8 SDF Download SDF
PubChem ID 5319322 Appearance Yellow powder
Formula C16H8O6 M.Wt 296.24
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES C1OC2=C(O1)C=C3C(=C2)C4=C(O3)C5=C(C=C(C=C5)O)OC4=O
Standard InChIKey URMVEUAWRUQHON-UHFFFAOYSA-N
Standard InChI InChI=1S/C16H8O6/c17-7-1-2-8-10(3-7)22-16(18)14-9-4-12-13(20-6-19-12)5-11(9)21-15(8)14/h1-5,17H,6H2
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Medicagol

The herbs of Medicago sativa

Protocol of Medicagol

Structure Identification
Journal of Organic Chemistry, 1965, 30(7):2353-2355.

Medicagol, a New Coumestan From Alfalfa.[Reference: WebLink]


METHODS AND RESULTS:
A new coumestan, Medicagol(C16H8O6), has been identified in alfalfa. Characterization was accomplished by degradative and proton magnetic resonance (p.m.r.) studies.
CONCLUSIONS:
Synthesis confirmed the structure as 7-hydroxy-11,12-methyl-enedioxycoumestan, closely related to the antifungal agent, pisatin.

Journal of Asian Natural Products Research, 2002, 4(1):1-5.

A new Coumaronochromone from Sophora japonica.[Reference: WebLink]


METHODS AND RESULTS:
A new coumaronochromone derivative, sophorophenolone (1), along with 13 known compounds, l-maackiain (2), Medicagol (3), 7-O-methylpseudobaptigenin (4), pseudobaptigenin (5), 7,3'-di-O-methylorobol (6), genistein (7), prunetin (8), daidzein (9), formononetin (10), Di-O-methyldaidzein (11), quercetin (12), kaempferol (13) and isorhamnetin (14) were isolated from pericarps of Sophorajaponica L.
CONCLUSIONS:
The structure of compound 1 was established by UV, IR, MS, and one-dimensional and two-dimensional NMR spectroscopy, including DEPT, NOESY, 1H-1H COSY, HMQC, and HMBC experiments.

Medicagol Dilution Calculator

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Medicagol Molarity Calculator

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Preparing Stock Solutions of Medicagol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3756 mL 16.8782 mL 33.7564 mL 67.5128 mL 84.391 mL
5 mM 0.6751 mL 3.3756 mL 6.7513 mL 13.5026 mL 16.8782 mL
10 mM 0.3376 mL 1.6878 mL 3.3756 mL 6.7513 mL 8.4391 mL
50 mM 0.0675 mL 0.3376 mL 0.6751 mL 1.3503 mL 1.6878 mL
100 mM 0.0338 mL 0.1688 mL 0.3376 mL 0.6751 mL 0.8439 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Medicagol

Phenolic Compounds from Cyclopia intermedia (Honeybush Tea). 1.[Pubmed:27403732]

J Agric Food Chem. 1998 Sep;46(9):3406-10.

The processed leaves and stems of Cyclopia intermedia contain 4-hydroxycinnamic acid, the isoflavones formononetin, afrormosin, calycosin, pseudobaptigen, and fujikinetin, the flavanones naringenin, eriodictyol, hesperitin, and hesperidin, the coumestans Medicagol, flemichapparin, and sophoracoumestan B, the xanthones mangiferin and isomangiferin, the flavone luteolin, and the inositol (+)-pinitol.

A new coumaronochromone from Sophora japonica.[Pubmed:11991186]

J Asian Nat Prod Res. 2002 Mar;4(1):1-5.

A new coumaronochromone derivative, sophorophenolone (1), along with 13 known compounds, l-maackiain (2), Medicagol (3), 7-O-methylpseudobaptigenin (4), pseudobaptigenin (5), 7,3'-di-O-methylorobol (6), genistein (7), prunetin (8), daidzein (9), formononetin (10), Di-O-methyldaidzein (11), quercetin (12), kaempferol (13) and isorhamnetin (14) were isolated from pericarps of Sophorajaponica L. The structure of compound 1 was established by UV, IR, MS, and one-dimensional and two-dimensional NMR spectroscopy, including DEPT, NOESY, 1H-1H COSY, HMQC, and HMBC experiments.

Description

Medicagol, is a natural compound isolated from Medicago sativa.

Keywords:

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