Oleoside

CAS# 178600-68-5

Oleoside

Catalog No. BCN1134----Order now to get a substantial discount!

Product Name & Size Price Stock
Oleoside: 5mg $828 In Stock
Oleoside: 10mg Please Inquire In Stock
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Quality Control of Oleoside

Number of papers citing our products

Chemical structure

Oleoside

3D structure

Chemical Properties of Oleoside

Cas No. 178600-68-5 SDF Download SDF
PubChem ID 101042548 Appearance Powder
Formula C16H22O11 M.Wt 390.3
Type of Compound Iridoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4S,5E,6S)-4-(carboxymethyl)-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylic acid
SMILES CC=C1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)O)CC(=O)O
Standard InChIKey PNMNSRMFRJNZFD-IPEIANHJSA-N
Standard InChI InChI=1S/C16H22O11/c1-2-6-7(3-10(18)19)8(14(23)24)5-25-15(6)27-16-13(22)12(21)11(20)9(4-17)26-16/h2,5,7,9,11-13,15-17,20-22H,3-4H2,1H3,(H,18,19)(H,23,24)/b6-2+/t7-,9+,11+,12-,13+,15-,16-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Oleoside

The herbs of Lepidium sativum

Biological Activity of Oleoside

Description1. Oleacein is a strong Angiotensin Converting Enzyme (ACE)-inhibitor (IC50 = 26 uM).

Oleoside Dilution Calculator

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Oleoside Molarity Calculator

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Preparing Stock Solutions of Oleoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5621 mL 12.8107 mL 25.6213 mL 51.2426 mL 64.0533 mL
5 mM 0.5124 mL 2.5621 mL 5.1243 mL 10.2485 mL 12.8107 mL
10 mM 0.2562 mL 1.2811 mL 2.5621 mL 5.1243 mL 6.4053 mL
50 mM 0.0512 mL 0.2562 mL 0.5124 mL 1.0249 mL 1.2811 mL
100 mM 0.0256 mL 0.1281 mL 0.2562 mL 0.5124 mL 0.6405 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Oleoside

Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea.[Pubmed:23194770]

Phytomedicine. 1996 Mar;2(4):319-25.

The aqueous extract of the leaves of Olea europaea and Olea lancea both inhibited Angiotensin Converting Enzyme (ACE) in vitro. A bioassay-directed fractionation resulted in the isolation of a strong ACE-inhibitor namely the secoiridoid 2-(3,4-dihydroxyphenyl)ethyl 4-formyl-3-(2-oxoethyl)-4 E-hexenoate (oleacein) (IC(50) = 26 muM). Five secoiridoid glycosides (oleuropein, ligstroside, excelcioside, Oleoside 11-methyl ester, Oleoside) isolated from Oleaceous plants showed no significant ACE-inhibition whereas, after enzymatic hydrolysis, the ACE-inhibition at 0.33 mg/ml was between 64% to 95%. Secoiridoids have not been described previously in the literature as inhibitors of ACE. Oleacein showed a low toxicity in the brine shrimp (Artemia satina) lethality test (LC(50) (24 h) = 969 ppm).

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