Polygalasaponin XXVIIICAS# 176182-01-7 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 176182-01-7 | SDF | Download SDF |
| PubChem ID | 197711.0 | Appearance | Powder |
| Formula | C53H84O24 | M.Wt | 1105.22 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S,3R,4S,4aR,6aR,6bR,8aS,12aS,14aR,14bR)-8a-[(2S,3R,4S,5R,6R)-3-[(2S,3R,4S,5R,6S)-3,4-dihydroxy-6-methyl-5-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-methyloxan-2-yl]oxycarbonyl-2-hydroxy-6b-(hydroxymethyl)-4,6a,11,11,14b-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid | ||
| SMILES | CC1C(C(C(C(O1)OC(=O)C23CCC(CC2C4=CCC5C(C4(CC3)CO)(CCC6C5(CC(C(C6(C)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)C)C)(C)C)OC8C(C(C(C(O8)C)OC9C(C(C(CO9)O)O)O)O)O)O)O | ||
| Standard InChIKey | KVWTUWYHUKDWNS-LHJNYBJOSA-N | ||
| Standard InChI | InChI=1S/C53H84O24/c1-21-30(58)34(62)40(75-43-38(66)35(63)39(22(2)72-43)74-42-36(64)31(59)26(57)19-70-42)45(71-21)77-47(69)52-13-12-48(3,4)16-24(52)23-8-9-28-49(5)17-25(56)41(76-44-37(65)33(61)32(60)27(18-54)73-44)51(7,46(67)68)29(49)10-11-50(28,6)53(23,20-55)15-14-52/h8,21-22,24-45,54-66H,9-20H2,1-7H3,(H,67,68)/t21-,22+,24+,25+,26-,27-,28-,29-,30+,31+,32-,33+,34+,35+,36-,37-,38-,39+,40-,41+,42+,43+,44+,45+,49-,50-,51+,52+,53+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Polygalasaponin XXVIII Dilution Calculator
Polygalasaponin XXVIII Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 0.9048 mL | 4.524 mL | 9.048 mL | 18.0959 mL | 22.6199 mL |
| 5 mM | 0.181 mL | 0.9048 mL | 1.8096 mL | 3.6192 mL | 4.524 mL |
| 10 mM | 0.0905 mL | 0.4524 mL | 0.9048 mL | 1.8096 mL | 2.262 mL |
| 50 mM | 0.0181 mL | 0.0905 mL | 0.181 mL | 0.3619 mL | 0.4524 mL |
| 100 mM | 0.009 mL | 0.0452 mL | 0.0905 mL | 0.181 mL | 0.2262 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- N-benzyl-heptadecanamide
Catalog No.:BCX0693
CAS No.:883715-19-3
- N-(3-methoxybenzyl)-octadecanamide
Catalog No.:BCX0692
CAS No.:1429659-99-3
- 8,9-epoxy-3,10-diisobutyryloxythymol
Catalog No.:BCX0691
CAS No.:22518-06-5
- Farnesene
Catalog No.:BCX0690
CAS No.:502-61-4
- Koumidine
Catalog No.:BCX0689
CAS No.:1358-75-4
- Gentianose
Catalog No.:BCX0688
CAS No.:25954-44-3
- 3-Hydroxy-1,2-dimethoxy-anthraquinone
Catalog No.:BCX0687
CAS No.:10383-62-7
- Cassiaside C2
Catalog No.:BCX0686
CAS No.:1958039-40-1
- Sequoyitol
Catalog No.:BCX0685
CAS No.:523-92-2
- Quinquenoside R1
Catalog No.:BCX0684
CAS No.:85013-02-1
- 2-hydroxyl emodin-1-methyl ether
Catalog No.:BCX0683
CAS No.:346434-45-5
- Maceneolignan H
Catalog No.:BCX0682
CAS No.:1314042-85-7
- Cavidine
Catalog No.:BCX0695
CAS No.:32728-75-9
- Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside]
Catalog No.:BCX0696
CAS No.:83048-35-5
- Desacylsenegasaponin B
Catalog No.:BCX0697
CAS No.:163589-51-3
- Myricetin 3-O-rutinoside
Catalog No.:BCX0698
CAS No.:41093-68-9
- Cyclanoline
Catalog No.:BCX0699
CAS No.:18556-27-9
- Cauloside D
Catalog No.:BCX0700
CAS No.:12672-45-6
- Methylcantharidinimide
Catalog No.:BCX0701
CAS No.:76970-78-0
- Mussaenosidic acid
Catalog No.:BCX0702
CAS No.:82451-22-7
- Epirosmanol
Catalog No.:BCX0703
CAS No.:93380-12-2
- Endothalic acid
Catalog No.:BCX0704
CAS No.:145-73-3
- Ginsenoside Ra6
Catalog No.:BCX0705
CAS No.:1346522-89-1
- Methyl jasmonate
Catalog No.:BCX0706
CAS No.:1211-29-6
[UPLC/Q-TOF MS and NMR plant metabolomics approach in studying the effect of growth year on the quality of Polygala tenuifolia].[Pubmed:26118115]
Yao Xue Xue Bao. 2015 Mar;50(3):340-7.
Growth year is one of the important factors for the quality of Polygala tenufolia. In this study, primary metabolites and secondary metabolites were compared in 1, 2 and 3 years old P. tenufolia cultivated in Shaanxi Heyang. The samples were subjected to ultra-high performance liquid chromatography (UPLC)-quadrupole time-of-flight mass spectrometry (Q-TOF MS) and nuclear magnetic resonance (NMR) analysis, and the obtained data were analyzed using principal component analysis (PCA) and other statistical analysis methods. In addition, content and correlation of different metabolites were also calculated. The results showed no significance between main component contents in 2 year-old and 3 year-old P. Tenufolia, but 1 year-old was statistically different. The contents of primary metabolites, such as fructose, sucrose, and choline increased as time goes on, while glycine and raffinose decreased. The contents of secondary metabolites, such as onjisaponin Fg, Polygalasaponin XXVIII, polygalasaponin XXXII increased, while polygalaxanthone III and parts of oligosaccharide multi-ester including tenuifoliose A, tenuifoliose C, tenuifoliose C2 and tenuifoliose H decreased with the extension of the growth years. Growth years has important impact on the quality of P. tenuifolia and the existing growing years of commodity P. tenuifolia have its scientific evidence. This study supplied a new method for the quality evaluation of Chinese medicinal materials.
Biologically active triterpene saponins from callus tissue of Polygala amarella.[Pubmed:10395523]
J Nat Prod. 1999 Jun;62(6):923-6.
A new bioactive saponin (1), together with a known saponin (Polygalasaponin XXVIII) has been isolated from the callus tissue culture of Polygala amarella. Based on spectroscopic data, especially direct and long-range heteronuclear 2D NMR analysis and on chemical transformations, the structure of 1 was elucidated as 3-O-beta-D-glucopyranosyl presenegenin-28-O-beta-D-galactopyranosyl-(1 --> 3)-beta-D-xylopyranosyl-(1 --> 4)-alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 3)]-beta-D-fucopyranoside. Both saponins showed significant immunological properties based on the enhancement of granulocyte phagocytosis in vitro.
