Raddeanoside 20

CAS# 335354-79-5

Raddeanoside 20

Catalog No. BCN2796----Order now to get a substantial discount!

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Raddeanoside 20: 5mg $213 In Stock
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Quality Control of Raddeanoside 20

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Chemical structure

Raddeanoside 20

3D structure

Chemical Properties of Raddeanoside 20

Cas No. 335354-79-5 SDF Download SDF
PubChem ID 102004861 Appearance Powder
Formula C47H76O17 M.Wt 913.1
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-6a-(hydroxymethyl)-10-[(2S,3R,4S,5S)-4-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,2,6b,9,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
SMILES CC1C(C(C(C(O1)OC2C(C(COC2OC3CCC4(C(C3(C)C)CCC5(C4CC=C6C5(CCC7(C6CC(CC7)(C)C)C(=O)O)CO)C)C)OC8C(C(C(C(O8)CO)O)O)O)O)O)O)O
Standard InChIKey RNHLYDFRRIHVAM-YUSSBOCDSA-N
Standard InChI InChI=1S/C47H76O17/c1-22-30(50)33(53)35(55)38(60-22)64-37-32(52)26(62-39-36(56)34(54)31(51)25(19-48)61-39)20-59-40(37)63-29-11-12-44(6)27(43(29,4)5)10-13-45(7)28(44)9-8-23-24-18-42(2,3)14-15-46(24,41(57)58)16-17-47(23,45)21-49/h8,22,24-40,48-56H,9-21H2,1-7H3,(H,57,58)/t22-,24-,25+,26-,27-,28+,29-,30-,31+,32-,33+,34-,35+,36+,37+,38-,39-,40-,44-,45+,46-,47-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Raddeanoside 20

The rhizomes of Anemone raddeana Regel

Biological Activity of Raddeanoside 20

Description1. Raddeanoside 20 can slightly suppress the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) in a concentration dependent manner.

Raddeanoside 20 Dilution Calculator

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Raddeanoside 20 Molarity Calculator

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Preparing Stock Solutions of Raddeanoside 20

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0952 mL 5.4759 mL 10.9517 mL 21.9034 mL 27.3793 mL
5 mM 0.219 mL 1.0952 mL 2.1903 mL 4.3807 mL 5.4759 mL
10 mM 0.1095 mL 0.5476 mL 1.0952 mL 2.1903 mL 2.7379 mL
50 mM 0.0219 mL 0.1095 mL 0.219 mL 0.4381 mL 0.5476 mL
100 mM 0.011 mL 0.0548 mL 0.1095 mL 0.219 mL 0.2738 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Raddeanoside 20

Antiperoxidation activity of triterpenoids from rhizome of Anemone raddeana.[Pubmed:19084054]

Fitoterapia. 2009 Mar;80(2):105-11.

Four triterpenoid compounds hederacolchiside E (1), hederasaponin B (2), Raddeanoside 20 (3) and raddeanoside 21 (4) were isolated from ethanol extracts of rhizome of Anemone raddeana Regel. The effects of these triterpenoids on superoxide generation, tyrosyl phosphorylation of proteins and translocation of cytosolic compounds, such as p47(phox), p67(phox) and Rac to the cell membrane in human neutrophils was investigated. The superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) was slightly suppressed by hederasaponin B, Raddeanoside 20 and raddeanoside 21 in a concentration dependent manner. The superoxide generation induced by arachidonic acid (AA) was suppressed by hederasaponin B and raddeanoside 21 significantly. fMLP- and AA-induced tyrosyl phosphorylation and translocation of the cytosolic proteins: p47(phox), p67(phox), and Rac to the cell membrane were suppressed in parallel with the suppression of stimulus-induced superoxide generation.

Description

Raddeanoside 20 is a triterpenoid isolated from the rhizome of Anemone raddeana. Raddeanoside 20 can suppresse superoxide generation.

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