Polpunonic acidCAS# 33600-93-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 33600-93-0 | SDF | Download SDF |
| PubChem ID | 169521 | Appearance | Powder |
| Formula | C30H48O3 | M.Wt | 456.71 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,4aS,6aS,6aR,6bS,8aS,9R,12aS,14aS,14bR)-2,4a,6a,6a,8a,9,14a-heptamethyl-10-oxo-3,4,5,6,6b,7,8,9,11,12,12a,13,14,14b-tetradecahydro-1H-picene-2-carboxylic acid | ||
| SMILES | CC1C(=O)CCC2C1(CCC3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)C | ||
| Standard InChIKey | WHWHDGKOSUKYOV-GDXNDQEESA-N | ||
| Standard InChI | InChI=1S/C30H48O3/c1-19-20(31)8-9-21-27(19,4)11-10-22-28(21,5)15-17-30(7)23-18-26(3,24(32)33)13-12-25(23,2)14-16-29(22,30)6/h19,21-23H,8-18H2,1-7H3,(H,32,33)/t19-,21+,22-,23+,25+,26+,27+,28-,29+,30-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Polpunonic acid is a natural product from Tripterygium wilfordii Hook.f. |
| Structure Identification | Canadian Journal of Chemistry, 1981, 59(17): 2677-2683.Cytotoxic diterpenes triptolide, tripdiolide, and cytotoxic triterpenes from tissue cultures of Tripterygium wilfordii[Reference: WebLink]
|
Polpunonic acid Dilution Calculator
Polpunonic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1896 mL | 10.9479 mL | 21.8957 mL | 43.7915 mL | 54.7393 mL |
| 5 mM | 0.4379 mL | 2.1896 mL | 4.3791 mL | 8.7583 mL | 10.9479 mL |
| 10 mM | 0.219 mL | 1.0948 mL | 2.1896 mL | 4.3791 mL | 5.4739 mL |
| 50 mM | 0.0438 mL | 0.219 mL | 0.4379 mL | 0.8758 mL | 1.0948 mL |
| 100 mM | 0.0219 mL | 0.1095 mL | 0.219 mL | 0.4379 mL | 0.5474 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- (-)-Bilobalide
Catalog No.:BCN1279
CAS No.:33570-04-6
- Cyclo(Phe-Leu)
Catalog No.:BCN2418
CAS No.:3354-31-2
- Raddeanoside 20
Catalog No.:BCN2796
CAS No.:335354-79-5
- iMAC2
Catalog No.:BCC2396
CAS No.:335166-36-4
- Bax channel blocker
Catalog No.:BCC2392
CAS No.:335165-68-9
- 6'-Iodoresiniferatoxin
Catalog No.:BCC7114
CAS No.:335151-55-8
- Luteinizing Hormone Releasing Hormone (LHRH)
Catalog No.:BCC1049
CAS No.:33515-09-2
- Fucoxanthin
Catalog No.:BCN2948
CAS No.:3351-86-8
- Substance P
Catalog No.:BCC6957
CAS No.:33507-63-0
- MEK inhibitor
Catalog No.:BCC1738
CAS No.:334951-92-7
- (S)-HexylHIBO
Catalog No.:BCC7167
CAS No.:334887-48-8
- HexylHIBO
Catalog No.:BCC7166
CAS No.:334887-43-3
- Myricanol
Catalog No.:BCN5258
CAS No.:33606-81-4
- Ispinesib (SB-715992)
Catalog No.:BCC2509
CAS No.:336113-53-2
- Britannilactone
Catalog No.:BCN3509
CAS No.:33620-72-3
- Desoxyrhapontigenin
Catalog No.:BCN6479
CAS No.:33626-08-3
- Britannin
Catalog No.:BCN2366
CAS No.:33627-28-0
- 1-O-Acetylbritannilactone
Catalog No.:BCN7715
CAS No.:33627-41-7
- (S)-(+)-Ketamine hydrochloride
Catalog No.:BCC7930
CAS No.:33643-47-9
- H-Thr-Obzl.HCl
Catalog No.:BCC2674
CAS No.:33645-24-8
- Secnidazole
Catalog No.:BCC4971
CAS No.:3366-95-8
- Hypophyllanthin
Catalog No.:BCN5259
CAS No.:33676-00-5
- 19,20-(E)-Vallesamine
Catalog No.:BCN5260
CAS No.:3368-87-4
- Pachypodol
Catalog No.:BCN5261
CAS No.:33708-72-4
Cytotoxic diterpenes triptolide, tripdiolide, and cytotoxic triterpenes from tissue cultures of Tripterygium wilfordii
Canadian Journal of Chemistry, 1981, 59(17): 2677-2683.
Plant tissue cultures of Tripterygium wilfordii Hook F produced the cytotoxic diterpene triepoxides tripdiolide (1) and triptolide (2) in yields that were 16 and 3 times greater, respectively, than those observed in the plant itself. Other diterpenes, dehydroabietic acid (3) and 15-hydroxy-18-norabieta-3,8,11,13-tetraene-3-oic acid methyl ester (4) were also isolated. Co-occuring in these cultures were the cytotoxic quinone-methides, celastrol (5), compound 6, and compound 7. Other triterpenes produced were oleanolic acid (8) and Polpunonic acid (9). β-Sitosterol (17) was also isolated. The proposed structure of 4 was confirmed by synthesis starting from compound 3. Cytotoxic data are reported, and a possible biosynthetic relationship among dehydroabietic acid, compound 4, and tripdiolide (1) is presented.
