Primulaverin

CAS# 154-61-0

Primulaverin

2D Structure

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3D structure

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Primulaverin

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Chemical Properties of Primulaverin

Cas No. 154-61-0 SDF Download SDF
PubChem ID 3083558 Appearance White powder
Formula C20H28O13 M.Wt 476.4
Type of Compound Organic acids & Esters Storage Desiccate at -20°C
Solubility Soluble in water; sparingly soluble in ethan
Chemical Name methyl 5-methoxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxybenzoate
SMILES COC1=CC(=C(C=C1)OC2C(C(C(C(O2)COC3C(C(C(CO3)O)O)O)O)O)O)C(=O)OC
Standard InChIKey CDWVFJJMYKSVHM-HSMQXHTESA-N
Standard InChI InChI=1S/C20H28O13/c1-28-8-3-4-11(9(5-8)18(27)29-2)32-20-17(26)15(24)14(23)12(33-20)7-31-19-16(25)13(22)10(21)6-30-19/h3-5,10,12-17,19-26H,6-7H2,1-2H3/t10-,12-,13+,14-,15+,16-,17-,19+,20-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Primulaverin Dilution Calculator

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Primulaverin Molarity Calculator

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Preparing Stock Solutions of Primulaverin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0991 mL 10.4954 mL 20.9908 mL 41.9815 mL 52.4769 mL
5 mM 0.4198 mL 2.0991 mL 4.1982 mL 8.3963 mL 10.4954 mL
10 mM 0.2099 mL 1.0495 mL 2.0991 mL 4.1982 mL 5.2477 mL
50 mM 0.042 mL 0.2099 mL 0.4198 mL 0.8396 mL 1.0495 mL
100 mM 0.021 mL 0.105 mL 0.2099 mL 0.4198 mL 0.5248 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Primulaverin

Phenolics in Primula veris L. and P. elatior (L.) Hill Raw Materials.[Pubmed:28835753]

Int J Anal Chem. 2017;2017:2871579.

Primula veris L. and Primula elatior (L.) Hill represent medicinal plants used for the production of herbal teas and preparations with antioxidant and expectorant activity. Flowers and roots of both species possess the same biological activity. In the presented study, raw materials of wild growing P. veris and P. elatior were compared in terms of the content and composition of phenolic compounds using a fast and simple HPLC-DAD method. The study showed that flowers of both species were rich in flavonoids. However, P. veris flowers were characterized with a distinctly higher content of isorhamnetin-3-O-glucoside, astragalin, and (+)-catechin, whereas P. elatior occurred to be a richer source of rutoside and isorhamnetin-3-O-rutinoside. Hyperoside was found exclusively in P. elatior flowers. Phenolic glycosides (primverin and Primulaverin) were identified only in the roots. Their content was about ten times higher in P. veris in comparison with P. elatior underground organs. The obtained results clearly show that both Primula species differ distinctly in terms of the content and composition of phenolic compounds. The compounds differentiating both species to the highest degree (hyperoside, in flowers, as well as primverin and Primulaverin, in the roots) may be useful chemical markers in the identification and evaluation of both species.

Analysis of phenolic glycosides and saponins in Primula elatior and Primula veris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry.[Pubmed:16297921]

J Chromatogr A. 2006 Apr 21;1112(1-2):218-23.

This paper describes the first liquid chromatographic method suitable for the simultaneous determination of bioactive compounds, saponins and phenolic glycosides, present in Primula elatior and Primula veris, including the NMR data of Primulaverin and primeverin. Optimum separations were obtained with a Synergi 4mum Fusion RP 80A column, using 0.025% TFA in water and 5% acetonitrile in methanol as mobile phase. Saponins were detected by evaporative light scattering detection (ELSD), whereas the phenolic glycosides were monitored by UV at 210 nm. The method was validated for repeatability (sigma(rel) or=97.1%) and sensitivity (LOD

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