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Sagittatoside B

CAS# 118525-36-3

Sagittatoside B

2D Structure

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Sagittatoside B: 5mg $615 In Stock
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Quality Control of Sagittatoside B

3D structure

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Sagittatoside B

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Chemical Properties of Sagittatoside B

Cas No. 118525-36-3 SDF Download SDF
PubChem ID 10146160 Appearance Yellow powder
Formula C32H38O14 M.Wt 646.64
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one
SMILES CC1C(C(C(C(O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O)O)C4=CC=C(C=C4)OC)OC5C(C(C(CO5)O)O)O)O)O
Standard InChIKey BVDGQVAUJNUPGW-JGSSSOFVSA-N
Standard InChI InChI=1S/C32H38O14/c1-13(2)5-10-17-18(33)11-19(34)21-24(38)29(27(44-28(17)21)15-6-8-16(41-4)9-7-15)45-32-30(25(39)22(36)14(3)43-32)46-31-26(40)23(37)20(35)12-42-31/h5-9,11,14,20,22-23,25-26,30-37,39-40H,10,12H2,1-4H3/t14-,20+,22-,23-,25+,26+,30+,31-,32-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Sagittatoside B

The herbs of Epimedium brevicornu Maxim.

Biological Activity of Sagittatoside B

DescriptionSagittatoside B is a natural product from Epimedium brevicornu Maxim.

Protocol of Sagittatoside B

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2014 Jan;39(2):235-9.

Study on preparation of sagittatoside B with epimedin B converted from cellulase.[Pubmed: 24761637]


METHODS AND RESULTS:
To prepare Sagittatoside B with epimedin B Hydrolyzed from cellulase. With the conversion ratio as the index, the effects of pH value, temperature, reaction time, dosage of enzyme and concentration of substrates on the conversion ratio were detected. L9 (3(4)) orthogonal design was adopted to optimize the preparation process. Hydrolyzed products were identified by MS, 1H-NMR, and 13C-NMR. The results showed that the optimum reaction conditions for the enzymatic hydrolysis were that the temperature was 50 degrees C, the reaction medium was pH 5.6 acetic acid-sodium acetate buffer solution, the concentration of substrates was 20 g x L(-1), the mass ratio between enzyme and substrate was 3: 5, and the relative molecular mass of the reaction product was 646.23. NMR data proved that the product was Sagittatoside B.
CONCLUSIONS:
The process is simple and reliable under mild reaction conditions, thus suitable for industrial production.

Sagittatoside B Dilution Calculator

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Preparing Stock Solutions of Sagittatoside B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5465 mL 7.7323 mL 15.4646 mL 30.9291 mL 38.6614 mL
5 mM 0.3093 mL 1.5465 mL 3.0929 mL 6.1858 mL 7.7323 mL
10 mM 0.1546 mL 0.7732 mL 1.5465 mL 3.0929 mL 3.8661 mL
50 mM 0.0309 mL 0.1546 mL 0.3093 mL 0.6186 mL 0.7732 mL
100 mM 0.0155 mL 0.0773 mL 0.1546 mL 0.3093 mL 0.3866 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on Sagittatoside B

Sagittatoside B is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii).

References:
[1]. Chen Y, et al. Role of intestinal hydrolase in the absorption of prenylated flavonoids present in Yinyanghuo. Molecules. 2011 Feb 1;16(2):1336-48.

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References on Sagittatoside B

[Study on preparation of sagittatoside B with epimedin B converted from cellulase].[Pubmed:24761637]

Zhongguo Zhong Yao Za Zhi. 2014 Jan;39(2):235-9.

To prepare Sagittatoside B with epimedin B Hydrolyzed from cellulase. With the conversion ratio as the index, the effects of pH value, temperature, reaction time, dosage of enzyme and concentration of substrates on the conversion ratio were detected. L9 (3(4)) orthogonal design was adopted to optimize the preparation process. Hydrolyzed products were identified by MS, 1H-NMR, and 13C-NMR. The results showed that the optimum reaction conditions for the enzymatic hydrolysis were that the temperature was 50 degrees C, the reaction medium was pH 5.6 acetic acid-sodium acetate buffer solution, the concentration of substrates was 20 g x L(-1), the mass ratio between enzyme and substrate was 3: 5, and the relative molecular mass of the reaction product was 646.23. NMR data proved that the product was Sagittatoside B. The process is simple and reliable under mild reaction conditions, thus suitable for industrial production.

Description

Sagittatoside B is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii).

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