Stavudine sodiumCAS# 134624-73-0 |
Related Products
- Fasudil
Catalog No.:BCC5262
CAS No.:103745-39-7
- Ro 31-8220
Catalog No.:BCC4295
CAS No.:125314-64-9
- Go 6976
Catalog No.:BCC3703
CAS No.:136194-77-9
- Sotrastaurin (AEB071)
Catalog No.:BCC3857
CAS No.:425637-18-9
- Saikosaponin B2
Catalog No.:BCN5916
CAS No.:58316-41-9
- K-252c
Catalog No.:BCC3706
CAS No.:85753-43-1
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 134624-73-0 | SDF | Download SDF |
| PubChem ID | 78358329 | Appearance | Powder |
| Formula | C10H11N2NaO4 | M.Wt | 246.2 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | d4T sodium | ||
| Solubility | Soluble in DMSO | ||
| Chemical Name | sodium;[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methanolate | ||
| SMILES | CC1=CN(C(=O)NC1=O)C2C=CC(O2)C[O-].[Na+] | ||
| Standard InChIKey | NPETYOHVRRLVHG-KZYPOYLOSA-N | ||
| Standard InChI | InChI=1S/C10H11N2O4.Na/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8;/h2-4,7-8H,5H2,1H3,(H,11,14,15);/q-1;+1/t7-,8+;/m0./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Stavudine sodium is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Target: HIV RT; NRTIs
Stavudine sodium is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Stavudine sodium is an analog of thymidine. It is phosphorylated by cellular kinases into active triphosphate. Stavudine sodium triphosphate inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It also causes termination of DNA synthesis by incorporating into it [1].
Mice were treated for 2 weeks with stavudine d4T (500 mg/kg/day), L-carnitine (200 mg/kg/day) or both drugs concomitantly. Body fatness was assessed by dual energy X-ray absorptiometry, and investigations were performed in plasma, liver, muscle and WAT. D4T reduced the gain of body adiposity, WAT leptin, whole body FAO and plasma ketone bodies, and increased liver triglycerides and plasma aminotransferases with mild ultrastructural abnormalities in hepatocytes [2].
Clinical indications: HIV-1 infection
FDA Approved Date: June 24, 1994
Toxicity: peripheral neuropathy; lipodystrophy References: | |||||
Stavudine sodium Dilution Calculator
Stavudine sodium Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.0617 mL | 20.3087 mL | 40.6174 mL | 81.2348 mL | 101.5435 mL |
| 5 mM | 0.8123 mL | 4.0617 mL | 8.1235 mL | 16.247 mL | 20.3087 mL |
| 10 mM | 0.4062 mL | 2.0309 mL | 4.0617 mL | 8.1235 mL | 10.1543 mL |
| 50 mM | 0.0812 mL | 0.4062 mL | 0.8123 mL | 1.6247 mL | 2.0309 mL |
| 100 mM | 0.0406 mL | 0.2031 mL | 0.4062 mL | 0.8123 mL | 1.0154 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Stavudine sodium is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Featured Products
- ML 218 hydrochloride
Catalog No.:BCC6207
CAS No.:1346233-68-8
- SA 57
Catalog No.:BCC6280
CAS No.:1346169-63-8
- Planchol E
Catalog No.:BCN6882
CAS No.:1346137-02-7
- LY2795050
Catalog No.:BCC1719
CAS No.:1346133-08-1
- ML 154
Catalog No.:BCC8022
CAS No.:1345964-89-7
- 5,7-Di-O-methylquercetin
Catalog No.:BCN3386
CAS No.:13459-07-9
- CYM 50308
Catalog No.:BCC6260
CAS No.:1345858-76-5
- Altiratinib
Catalog No.:BCC6385
CAS No.:1345847-93-9
- Arginase inhibitor 1
Catalog No.:BCC4034
CAS No.:1345808-25-4
- ETP-46464
Catalog No.:BCC3913
CAS No.:1345675-02-6
- AM095
Catalog No.:BCC1351
CAS No.:1345614-59-6
- Atorvastatin Calcium
Catalog No.:BCC2319
CAS No.:134523-03-8
New Products
- Eriocitrin
Catalog No.:BCN1208
CAS No.:13463-28-0
- Zinc Pyrithione
Catalog No.:BCC5008
CAS No.:13463-41-7
- ML 240
Catalog No.:BCC5604
CAS No.:1346527-98-7
- GSK503
Catalog No.:BCC6386
CAS No.:1346572-63-1
- GSK126
Catalog No.:BCC1604
CAS No.:1346574-57-9
- GSK621
Catalog No.:BCC6517
CAS No.:1346607-05-3
- GSK343
Catalog No.:BCC1607
CAS No.:1346704-33-3
- Lamivudine
Catalog No.:BCC3801
CAS No.:134678-17-4
- Linderane
Catalog No.:BCN5023
CAS No.:13476-25-0
- A 412997 dihydrochloride
Catalog No.:BCC6224
CAS No.:1347744-96-0
- 6''-O-Acetylglycitin
Catalog No.:BCN3866
CAS No.:134859-96-4
- 8-M-PDOT
Catalog No.:BCC6901
CAS No.:134865-70-6
Stavudine sodium is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Stavudine sodium,134624-73-0,d4T sodium,Natural Products,HIV, buy Stavudine sodium , Stavudine sodium supplier , purchase Stavudine sodium , Stavudine sodium cost , Stavudine sodium manufacturer , order Stavudine sodium , high purity Stavudine sodium
