Stigmast-4-ene-3,6-diolCAS# 113626-76-9 |
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| Cas No. | 113626-76-9 | SDF | Download SDF |
| PubChem ID | 10550610 | Appearance | Powder |
| Formula | C29H50O2 | M.Wt | 430.7 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (3S,6R,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol | ||
| SMILES | CCC(CCC(C)C1CCC2C1(CCC3C2CC(C4=CC(CCC34C)O)O)C)C(C)C | ||
| Standard InChIKey | OOUCIUZOGLWLAN-NDDUEHJASA-N | ||
| Standard InChI | InChI=1S/C29H50O2/c1-7-20(18(2)3)9-8-19(4)23-10-11-24-22-17-27(31)26-16-21(30)12-14-29(26,6)25(22)13-15-28(23,24)5/h16,18-25,27,30-31H,7-15,17H2,1-6H3/t19-,20-,21+,22+,23-,24+,25+,27-,28-,29-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The barks of Ailanthus altissima
| Description | 1. Stigmast-4-ene-3beta,6beta-diol possesses marked inhibitory activity against 12-O- -tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. |
Stigmast-4-ene-3,6-diol Dilution Calculator
Stigmast-4-ene-3,6-diol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3218 mL | 11.609 mL | 23.218 mL | 46.436 mL | 58.045 mL |
| 5 mM | 0.4644 mL | 2.3218 mL | 4.6436 mL | 9.2872 mL | 11.609 mL |
| 10 mM | 0.2322 mL | 1.1609 mL | 2.3218 mL | 4.6436 mL | 5.8045 mL |
| 50 mM | 0.0464 mL | 0.2322 mL | 0.4644 mL | 0.9287 mL | 1.1609 mL |
| 100 mM | 0.0232 mL | 0.1161 mL | 0.2322 mL | 0.4644 mL | 0.5805 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Inhibitory effect of some oxygenated stigmastane-type sterols on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.[Pubmed:8593493]
Biol Pharm Bull. 1995 Nov;18(11):1617-9.
The oxygenated stigmastane-type sterols stigmastane-3 beta, 6 alpha-diol, stigmastane-3 beta, 6 beta-diol, 7 alpha-hydroxysitosterol and its diacetyl derivative, 7 beta-hydroxysitosterol and its diacetyl derivative, 7-oxositosterol, 4 beta-hydroxysitosterol, and stigmast-4-ene-3 beta, 6 beta-diol were evaluated with respect to their anti-inflammatory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. All of the sterols, with the exception of 7 alpha-hydroxysitosterol and its diacetyl derivative, were found to possess marked inhibitory activity. The 50% inhibitory dose of these compounds for TPA-inflammation (1 microgram) was 0.5--1.0 mg/ear.
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