Ustusolate A

CAS# 1136611-58-9

Ustusolate A

Catalog No. BCN6756----Order now to get a substantial discount!

Product Name & Size Price Stock
Ustusolate A: 5mg $1225 In Stock
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Quality Control of Ustusolate A

Number of papers citing our products

Chemical structure

Ustusolate A

3D structure

Chemical Properties of Ustusolate A

Cas No. 1136611-58-9 SDF Download SDF
PubChem ID 23843911 Appearance Oil
Formula C23H34O5 M.Wt 390.52
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1R,4S,4aS,8aS)-4-hydroxy-3,4-bis(hydroxymethyl)-4a,8,8-trimethyl-5,6,7,8a-tetrahydro-1H-naphthalen-1-yl] (2E,4E,6E)-octa-2,4,6-trienoate
SMILES CC=CC=CC=CC(=O)OC1C=C(C(C2(C1C(CCC2)(C)C)C)(CO)O)CO
Standard InChIKey VYUGROORELIDOB-MOHQOPMHSA-N
Standard InChI InChI=1S/C23H34O5/c1-5-6-7-8-9-11-19(26)28-18-14-17(15-24)23(27,16-25)22(4)13-10-12-21(2,3)20(18)22/h5-9,11,14,18,20,24-25,27H,10,12-13,15-16H2,1-4H3/b6-5+,8-7+,11-9+/t18-,20+,22+,23-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ustusolate A

The Aspergillus ustus

Biological Activity of Ustusolate A

Description1. Ustusolate A shows weak cytotoxicity against HL-60 and A549 cells with IC50 values of 20.6 and 30.0 microM, respectively.

Ustusolate A Dilution Calculator

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Ustusolate A Molarity Calculator

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Preparing Stock Solutions of Ustusolate A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5607 mL 12.8034 mL 25.6069 mL 51.2138 mL 64.0172 mL
5 mM 0.5121 mL 2.5607 mL 5.1214 mL 10.2428 mL 12.8034 mL
10 mM 0.2561 mL 1.2803 mL 2.5607 mL 5.1214 mL 6.4017 mL
50 mM 0.0512 mL 0.2561 mL 0.5121 mL 1.0243 mL 1.2803 mL
100 mM 0.0256 mL 0.128 mL 0.2561 mL 0.5121 mL 0.6402 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ustusolate A

Sesquiterpenoids and benzofuranoids from the marine-derived fungus Aspergillus ustus 094102.[Pubmed:19769341]

J Nat Prod. 2009 Oct;72(10):1761-7.

Eight drimane sesquiterpenes (1-8), six isochromane derivatives (9-14), and three known compounds, daldinin B (15), 9alpha-hydroxy-6beta-[(2E,4E,6E)-octa-2,4,6-trienoyloxy]-5alpha-drim-7-en-11,12-o lide (16), and pergillin (17), were isolated from the EtOAc extract of the marine-derived fungus Aspergillus ustus 094102. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. The cytotoxic effects on A549 and HL-60 cell lines were evaluated by SRB and MTT methods. Ustusorane E (13) showed significant cytotoxicity against HL-60 cells with an IC50 value of 0.13 microM. Ustusolates C (6) and E (8) exhibited moderate cytotoxicity against A549 and HL-60 cells with IC50 values of 10.5 and 9.0 microM, respectively, and Ustusolate A (4) showed weak cytotoxicity against HL-60 and A549 cells with IC50 values of 20.6 and 30.0 microM, respectively.

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