TCS 2210Inducer of neuronal differentiation in MSCs CAS# 1201916-31-5 |
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Quality Control & MSDS
3D structure
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| Cas No. | 1201916-31-5 | SDF | Download SDF |
| PubChem ID | 75080768 | Appearance | Powder |
| Formula | C18H17N3O3 | M.Wt | 323.35 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 50 mM in DMSO | ||
| Chemical Name | N-hydroxy-2-oxo-3-(3-phenylpropyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-quinoxaline-6-carboxamide | ||
| SMILES | C1CC2C(CC1C(=O)NO)NC(C(=O)N2)CCCC3=CC=CC=C3 | ||
| Standard InChIKey | CSPOZLMUZAZKQV-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C18H25N3O3/c22-17(21-24)13-9-10-14-16(11-13)19-15(18(23)20-14)8-4-7-12-5-2-1-3-6-12/h1-3,5-6,13-16,19,24H,4,7-11H2,(H,20,23)(H,21,22) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Inducer of neuronal differentiation in mesenchymal stem cells (MSCs) with specific phenotype change. Increases expression of neuronal markers β-III tubulin and NSE without cytotoxicity. |
TCS 2210 Dilution Calculator
TCS 2210 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.0926 mL | 15.4631 mL | 30.9262 mL | 61.8525 mL | 77.3156 mL |
| 5 mM | 0.6185 mL | 3.0926 mL | 6.1852 mL | 12.3705 mL | 15.4631 mL |
| 10 mM | 0.3093 mL | 1.5463 mL | 3.0926 mL | 6.1852 mL | 7.7316 mL |
| 50 mM | 0.0619 mL | 0.3093 mL | 0.6185 mL | 1.237 mL | 1.5463 mL |
| 100 mM | 0.0309 mL | 0.1546 mL | 0.3093 mL | 0.6185 mL | 0.7732 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Discovery of a new and efficient small molecule for neuronal differentiation from mesenchymal stem cell.[Pubmed:20014867]
J Med Chem. 2009 Dec 24;52(24):7931-3.
A new synthetic small molecule, compound 1, which induced a neuronal differentiation from mesenchymal stem cells (MSCs) with an excellent efficiency, was identified. Furthermore the differentiated cell by 1 showed the neural electrophysiological and cholinergic neuron properties.
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