Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 20

  1. Cat.No. Product Name Information/Activity
  2. BCC6949 CGP 12177 hydrochloride 64208-32-8 CGP 12177 hydrochloride chemical structure
  3. BCC7091 CL 316243 disodium salt 151126-84-0 CL 316243 disodium salt chemical structure
  4. BCC5688 ICI 215,001 hydrochloride 140850-02-8 ICI 215,001 hydrochloride chemical structure
  5. BCC7282 L-755,507 L755507 is a potent, selective agonist of β3-AR with an IC50 of 35 nM. L-755,507 chemical structure
  6. BCC6881 Pindolol Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM). Pindolol chemical structure
  7. BCC7833 SR 58611A hydrochloride Amibegron hydrochloride is a selective β3-adrenoceptor agonist, with an EC50 of 3.5 nM for β-adrenoceptor in rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity. SR 58611A hydrochloride chemical structure
  8. BCC5878 ZD 2079 178600-17-4 ZD 2079 chemical structure
  9. BCC6852 ZD 7114 hydrochloride 129689-28-7 ZD 7114 hydrochloride chemical structure
  10. BCC7475 L-748,337 244192-94-7 L-748,337 chemical structure
  11. BCC7094 SR 59230A hydrochloride SR59230A hydrochloride is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively. SR 59230A hydrochloride chemical structure

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