Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 13

  1. Cat.No. Product Name Information/Activity
  2. BCC7101 LY 215840 137328-52-0 LY 215840 chemical structure
  3. BCC5937 SB 258719 hydrochloride 1217674-10-6 SB 258719 hydrochloride chemical structure
  4. BCC5056 SB269970 HCl SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors. SB269970 HCl chemical structure
  5. BCC6681 8-Hydroxy-DPAT hydrobromide 76135-31-4 8-Hydroxy-DPAT hydrobromide chemical structure
  6. BCC6266 LP 20 hydrochloride 1386928-34-2 LP 20 hydrochloride chemical structure
  7. BCC6912 A 61603 hydrobromide 107756-30-9 A 61603 hydrobromide chemical structure
  8. BCC6833 Cirazoline hydrochloride Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM). Cirazoline hydrochloride chemical structure
  9. BCC4333 Oxymetazoline HCl 2315-02-8 Oxymetazoline HCl chemical structure
  10. BCC4335 Phenylephrine HCl (R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively. Phenylephrine HCl chemical structure
  11. BCC2494 Alfuzosin HCl Alfuzosin hydrochloride is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH). Alfuzosin HCl chemical structure

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