Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 7

  1. Cat.No. Product Name Information/Activity
  2. BCC4402 Felodipine Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. Felodipine chemical structure
  3. BCC4398 Flunarizine 2HCl Flunarizine is a selective calcium entry blocker. Flunarizine 2HCl chemical structure
  4. BCC8041 Huwentoxin XVI Potent and reversible N-type Ca<sup>2+</sup> channel blocker Huwentoxin XVI chemical structure
  5. BCC3797 Isradipine (Dynacirc) Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM. Isradipine (Dynacirc) chemical structure
  6. BCC7561 L-651,582 Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole shows anti-tumor, anti-inflammatory and antiangiogenic effects. L-651,582 chemical structure
  7. BCC5238 Lercanidipine hydrochloride Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class. Lercanidipine hydrochloride chemical structure
  8. BCC4380 Loperamide HCl Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist. Loperamide hydrochloride is a selective and competitive Loperamide HCl chemical structure
  9. BCC1749 Mibefradil dihydrochloride Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively. Mibefradil dihydrochloride chemical structure
  10. BCC4808 Nifedipine Nifedipine (BAY-a-1040) is a potent calcium channel blocker and drug of choice for cardiac insufficiencies. Nifedipine chemical structure
  11. BCC6947 (S)-(+)-Niguldipine hydrochloride 113145-69-0 (S)-(+)-Niguldipine hydrochloride chemical structure

Items 61 to 70 of 631 total