Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 9

  1. Cat.No. Product Name Information/Activity
  2. BCN2207 Ascorbic acid PROTAC EED degrader-1 is a PROTAC targeting EED with a pKD of 9.02. PROTAC EED degrader-1 is a polycomb repressive complex 2 (PRC2) inhibitor (pIC50=8.17) targeting the EED subunit. Ascorbic acid chemical structure
  3. BCC3783 Gabapentin Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. Gabapentin chemical structure
  4. BCN2175 Pregabalin 148553-50-8 Pregabalin chemical structure
  5. BCC7928 BIMU 8 Potent 5-HT<sub>4</sub> receptor full agonist BIMU 8 chemical structure
  6. BCC4207 Cisapride 81098-60-4 Cisapride chemical structure
  7. BCC7562 CJ 033466 519148-48-2 CJ 033466 chemical structure
  8. BCC7695 ML 10302 hydrochloride 186826-17-5 ML 10302 hydrochloride chemical structure
  9. BCC1065 Mosapride Citrate Mosapride citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist. Mosapride Citrate chemical structure
  10. BCC6771 2-[1-(4-Piperonyl)piperazinyl]benzothiazole 155106-73-3 2-[1-(4-Piperonyl)piperazinyl]benzothiazole chemical structure
  11. BCC5693 RS 67333 hydrochloride 168986-60-5 RS 67333 hydrochloride chemical structure

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