Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 12

  1. Cat.No. Product Name Information/Activity
  2. BCC7216 SB 258585 hydrochloride 1216468-02-8 SB 258585 hydrochloride chemical structure
  3. BCC1924 SB 271046 hydrochloride SB271046 Hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9. SB 271046 hydrochloride chemical structure
  4. BCC7750 SGS 518 oxalate 445441-27-0 SGS 518 oxalate chemical structure
  5. BCC6709 Metergoline Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors. Metergoline chemical structure
  6. BCC5663 2-Methyl-5-hydroxytryptamine hydrochloride 2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects. 2-Methyl-5-hydroxytryptamine hydrochloride chemical structure
  7. BCC1114 Mianserin HCl Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant. Mianserin HCl chemical structure
  8. BCC7218 AS 19 AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia. AS 19 chemical structure
  9. BCC7517 LP 12 hydrochloride 1185136-22-4 LP 12 hydrochloride chemical structure
  10. BCC7399 LP 44 824958-12-5 LP 44 chemical structure
  11. BCC7990 DR 4485 hydrochloride 402942-53-4 DR 4485 hydrochloride chemical structure

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