Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 8

  1. Cat.No. Product Name Information/Activity
  2. BCC3799 Nilvadipine Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM. Nilvadipine chemical structure
  3. BCC3823 Nimodipine Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine chemical structure
  4. BCC4381 Nitrendipine Nitrendipine is a calcium channel blocker with marked vasodilator action. Nitrendipine chemical structure
  5. BCC1803 NNC 55-0396 NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. NNC 55-0396 chemical structure
  6. BCC7706 PD 173212 PD173212 is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays. PD 173212 chemical structure
  7. BCC6255 ProTx I 484598-35-8 ProTx I chemical structure
  8. BCC7067 Ruthenium Red 11103-72-3 Ruthenium Red chemical structure
  9. BCC5952 SNX 482 203460-30-4 SNX 482 chemical structure
  10. BCC7181 SR 33805 oxalate 121346-33-6 SR 33805 oxalate chemical structure
  11. BCC4747 Verapamil HCl Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel antagonist. Verapamil HCl chemical structure

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