Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 2

  1. Cat.No. Product Name Information/Activity
  2. BCC4486 Mifepristone Mifepristone is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay. Mifepristone chemical structure
  3. BCC4767 Budesonide Budesonide is a glucocortical steroid with potent anti-inflammatory activity. Budesonide chemical structure
  4. BCC1184 Dexamethasone (DHAP) Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18L expression on monocytes. Dexamethasone (DHAP) chemical structure
  5. BCN2192 Hydrocortisone Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland. Hydrocortisone chemical structure
  6. BCC7640 8-(3-Chlorostyryl)caffeine 147700-11-6 8-(3-Chlorostyryl)caffeine chemical structure
  7. BCC6786 Bifemelane hydrochloride 62232-46-6 Bifemelane hydrochloride chemical structure
  8. BCC5196 R-(-)-Deprenyl hydrochloride R-(-)-Deprenyl Hydrochloride is a selective inhibitor of monoamine oxidase B (MAO-B). R-(-)-Deprenyl hydrochloride chemical structure
  9. BCN3998 Harman 486-84-0 Harman chemical structure
  10. BCC7371 Lazabemide hydrochloride 103878-83-7 Lazabemide hydrochloride chemical structure
  11. BCC2322 Moclobemide (Ro 111163) Moclobemide(Ro111163) is a reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Moclobemide (Ro 111163) chemical structure

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