Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 10

  1. Cat.No. Product Name Information/Activity
  2. BCC6878 RS 67506 hydrochloride 5-HT<sub>4</sub> partial agonist RS 67506 hydrochloride chemical structure
  3. BCC7955 Tegaserod maleate Tegaserod maleate is a partial agonist of the 5-HT4 receptor; stimulates the peristaltic reflex and accelerates gastrointestinal transit. Tegaserod maleate chemical structure
  4. BCC7178 Zacopride hydrochloride 101303-98-4 Zacopride hydrochloride chemical structure
  5. BCC7019 GR 113808 GR 113808 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. GR 113808 chemical structure
  6. BCC7142 GR 125487 sulfamate 859502-43-5 GR 125487 sulfamate chemical structure
  7. BCC6767 RS 23597-190 hydrochloride 149719-06-2 RS 23597-190 hydrochloride chemical structure
  8. BCC5694 RS 39604 hydrochloride 167710-87-4 RS 39604 hydrochloride chemical structure
  9. BCC5673 SB 203186 hydrochloride 207572-69-8 SB 203186 hydrochloride chemical structure
  10. BCC5752 SB 204070 148688-01-1 SB 204070 chemical structure
  11. BCC7246 SDZ 205-557 hydrochloride 1197334-02-3 SDZ 205-557 hydrochloride chemical structure

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