Stress and Anxiety Research

Stress is a valuable evolutionary-conserved physiological response to threatening or adverse environments. Chronic stress is a pathological state that is caused by prolonged upregulation of the normal acute stress response. Anxiety disorders, such as phobias and post-traumatic stress disorder, are due to fear conditioning to a neutral stimulus and involve many of the same brain regions as stress.

Stress and Anxiety Research Products Targets

Products for Stress and Anxiety Research - Page 16

Cat.No. Product Name Information/Activity
BCN2181 Pramipexole dihydrochloride Pramipexole dihydrochloride is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
BCC7193 Eticlopride hydrochloride 97612-24-3
BCC7025 Nafadotride 149649-22-9
BCC7435 NGB 2904 189061-11-8
BCC7801 PG 01037 dihydrochloride 675599-62-9
BCC7664 PNU 177864 hydrochloride 250266-51-4
BCC7887 SB 277011A dihydrochloride SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively.
BCC7029 U 99194 maleate 234757-41-6
BCC6224 A 412997 dihydrochloride Selective D<sub>4</sub> agonist
BCC7293 ABT 724 trihydrochloride ABT-724 trihydrochloride is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM for human dopamine D4 receptor. ABT-724 trihydrochloride is a potent partial agonist at the rat D4 (EC50 of 14.3 nM) and the ferret D4 receptor (EC50 of 23.2 nM), and has no effect on dopamine D1, D2, D3, or D5 receptors. ABT-724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side-effect profile.