Stress and Anxiety Research
Stress is a valuable evolutionary-conserved physiological response to threatening or adverse environments. Chronic stress is a pathological state that is caused by prolonged upregulation of the normal acute stress response. Anxiety disorders, such as phobias and post-traumatic stress disorder, are due to fear conditioning to a neutral stimulus and involve many of the same brain regions as stress.
Stress and Anxiety Research Products Targets
- Others (13)
- D4 Receptor (12)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- AMPA Receptor (45)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- D3 Receptor (12)
- NMDA Receptor (87)
- Kainate Receptor (22)
- D2 Receptor (14)
- D1 and D5 Receptor (16)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
Products for Stress and Anxiety Research - Page 19
- Cat.No. Product Name Information/Activity
-
BCC6803
THIP hydrochloride
Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid analgesic and has hypnotic activities.
-
BCC6169
TP 003
628690-75-5
-
BCC6563
ZAPA sulfate
371962-01-5
-
BCC7387
(-)-Bicuculline methiodide
40709-69-1
-
BCC6555
(-)-Bicuculline methobromide
(-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABAA receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons.
-
BCN3763
(-)-Bicuculline methochloride
(-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons.
-
BCN1238
(+)-Bicuculline
(+)-Bicuculline is a light-sensitive competitive antagonist of GABA-A receptor.
-
BCC3782
Furosemide
Furosemide is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.
-
BCC6193
PHP 501 trifluoroacetate
1236105-75-1
-
BCC5705
Picrotoxin
Picrotoxin (Cocculin) is a natural noncompetitive antagonist of GABAA receptor, binds to the interface pocket on the GABAR. Picrotoxin (Cocculin) causes overstimulation and induces convulsions.


