Stress and Anxiety Research

Stress is a valuable evolutionary-conserved physiological response to threatening or adverse environments. Chronic stress is a pathological state that is caused by prolonged upregulation of the normal acute stress response. Anxiety disorders, such as phobias and post-traumatic stress disorder, are due to fear conditioning to a neutral stimulus and involve many of the same brain regions as stress.

Stress and Anxiety Research Products Targets

Products for Stress and Anxiety Research - Page 20

Cat.No. Product Name Information/Activity
BCC7266 SCS 3232-36-8
BCC6997 SR 95531 hydrobromide Gabazine is a selective and competitive antagonist of GABAA receptor, with an IC50 of ~0.2 μM for GABA receptor.
BCC7510 TB 21007 207306-50-1
BCC7471 U 93631 U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors.
BCC5521 Emapunil Emapunil(AC-5216;XBD-173) is a translocator protein [TSPO (18 kDa)] ligand.
BCC7711 Bretazenil 84379-13-5
BCC6635 β-CCB 84454-35-3
BCC7162 CL 218872 66548-69-4
BCC6671 Dihydroergotoxine mesylate Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site.
BCC7560 DMCM hydrochloride DMCM hydrochloride is a nonselective full inverse agonist of benzodiazepine. DMCM shows bnding afinity at human recombinant GABAA αxβ3γ2 receptor subtypes with Kis of 10 nM, 13 nM, 7.5 nM, 2.2 nM for α1, α2, α3, and α5 receptors, respectively.