Products with
Cytotoxic bioactivity
Cat.No.
|
Product Name
|
BCN5076 |
6-Acetonyldihydrochelerythrine
|
1. 6-Acetonyldihydrochelerythrine exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively.
2. 6-Acetonyldihydrochelerythrine is a potent inducer of apoptosis in HCT116 and SW620 cell lines, it displays potent cytotoxic activity in human HCT116 and SW620 colon carcinoma cells, to a higher extent than 5-fluorouracil (5-FU), the cornerstone chemotherapeutic agent in colon cancer.
3. 6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities. |
BCN5111 |
Aglinin A
|
1. Aglinin A displays moderate cytotoxicity against all the three cancer cell lines((NCI-H187), epidermoid carcinoma (KB) and breast cancer (BC) cell lines). |
BCN5145 |
2,3-Dihydroxy-12-oleanen-28-oic acid
|
1. 2,3-Dihydroxy-olean-12-en-28-oic acids show a low cytotoxicity towards several human tumor cell lines. |
BCN5151 |
Coronalolide methyl ester
|
1. Coronalolide methyl ester and coronalolide show broad cytotoxic activity against a panel of human cancer cell lines.
2. Coronalolide methyl ester displays significant anti-HIV activities in the HIV-1RT assay. |
BCN5152 |
Coronalolide
|
1. Coronalolide and coronalolide methyl ester show broad cytotoxic activity against a panel of human cancer cell lines.
2. Coronalolide shows significant cytotoxic activities in P-388 cell line, it also displays significant anti-HIV activities in the HIV-1RT assay. |