Products with Cytotoxic bioactivity

Cat.No. Product Name
BCN5076 6-Acetonyldihydrochelerythrine
1. 6-Acetonyldihydrochelerythrine exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively. 2. 6-Acetonyldihydrochelerythrine is a potent inducer of apoptosis in HCT116 and SW620 cell lines, it displays potent cytotoxic activity in human HCT116 and SW620 colon carcinoma cells, to a higher extent than 5-fluorouracil (5-FU), the cornerstone chemotherapeutic agent in colon cancer. 3. 6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities.
BCN5111 Aglinin A
1. Aglinin A displays moderate cytotoxicity against all the three cancer cell lines((NCI-H187), epidermoid carcinoma (KB) and breast cancer (BC) cell lines).
BCN5145 2,3-Dihydroxy-12-oleanen-28-oic acid
1. 2,3-Dihydroxy-olean-12-en-28-oic acids show a low cytotoxicity towards several human tumor cell lines.
BCN5151 Coronalolide methyl ester
1. Coronalolide methyl ester and coronalolide show broad cytotoxic activity against a panel of human cancer cell lines. 2. Coronalolide methyl ester displays significant anti-HIV activities in the HIV-1RT assay.
BCN5152 Coronalolide
1. Coronalolide and coronalolide methyl ester show broad cytotoxic activity against a panel of human cancer cell lines. 2. Coronalolide shows significant cytotoxic activities in P-388 cell line, it also displays significant anti-HIV activities in the HIV-1RT assay.

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