Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5255 | 8-Deoxygartanin |
| 1. 8-Deoxygartanin inhibits p65 activation with IC50 values of 11.3 microM. 2. 8-Deoxygartanin has cytotoxic effect on human melanoma cells, it is a potential candidate as anti-melanoma agents. 3. 8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor. 4. 8-Deoxygartanin exhibits significant inhibition of self-induced β-amyloid (Aβ) aggregation, it has multifunctional activities against Alzheimer's disease (AD) and could be promising compounds for the therapy of AD. 5. 8-Deoxygartanin has antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs. 6. 8-Deoxygartanin at 5 ug/ml can increase the cell cycle arrest in G(1) phase compared with untreated cells . | |
| BCN5258 | Myricanol |
| 1. Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells. 2. Myricanol can significantly decelerate tumor growth in vivo by inducing apoptosis. | |
| BCN5261 | Pachypodol |
| 1. Pachypodol has cytotoxic potential ,can inhibit the growth of CaCo 2 colon cancer cell line in vitro. 2. Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida galabrata. 3. Pachypodol exhibits anti-emetic effects. 4. Pachypodol inhibits the water-splitting enzyme activity. | |
| BCN5265 | 7-Oxodehydroabietinol |
| 1. 7-Oxodehydroabietinol shows moderate cytotoxicity against a human lung carcinoma cell line. 2. 7-Oxodehydroabietinol exhibits significant antibacterial activity against gram (±) bacteria. | |
| BCN5293 | 9-Hydroxycalabaxanthone |
| 9-Hydroxycalabaxanthone exhibits cytotoxicity against the HT-29 cell line with ED50 values of 9.1 microM. The combination of 9-hydroxycalabaxanthone with α-mangostin shows the synergistic antimalarial interaction in both clones. | |
