Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4924 | 1-Decarboxy-3-oxo-ceanothic acid |
| 1. 1-Decarboxy-3-oxo-ceanothic acid shows in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, the cytotoxic effect is mediated, at least in part, by the induction of apoptosis. 2. 1-Decarboxy-3-oxo-ceanothic acid shows cytotoxic against OVCAR-3 and HeLa cancer cell lines, with an IC50 of 2.8 and 6.6 microg/mL, respectively, and an IC50 of 11.3 microg/mL against normal cell line FS-5. | |
| BCN4926 | 23-deoxojessic acid |
| 1. 23-Deoxojessic acid possesses strong cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 values equal to or less than 6 microM. | |
| BCN4941 | Eichlerialactone |
| 1. Eichlerialactone and ethyl eichlerianoate show antimycobacterial activity against mycobacterium tuberculosis H37Ra, with minimum inhibitory concentration in the range of 25–50ug/mL. 2. Eichlerialactone is weakly cytotoxic to a breast cancer (BC) cell line. 3. Eichlerialactone exhibits good antibacterial activity against both the Gram-positive pathogens. | |
| BCN4946 | Erysubin A |
| 1. Erysubin A , wighteone, and lupalbigenin show promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM). | |
| BCN4965 | Beta-Carotene |
| Beta Carotene is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A. Beta-Carotene has antioxidant activity, anti-cancer, and antiapoptotic activities, it has protective effects against gamma-radiation-induced in vivo chromosomal damage. Dietary supplementation of carotenoids may act as moderate hypocholesterolemic agents, secondary to their inhibitory effect on macrophage 3-hydroxy-3-methyl glutaryl coenzyme A (HMGCoA) reductase, the rate limiting enzyme in cholesterol synthesis. | |
