Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5696 | Murralongin |
| 1. Murralongin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. | |
| BCN5709 | 1-Hydroxyrutaecarpine |
| 1. 1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro. 2. 1-Hydroxyrutaecarpine exhibits antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 micrograms/ml. 3. 1-Hydroxyrutaecarpine displays moderate inhibitory activity on those enzymes(Cathepsins B, L and K) at the concentration of 125 ug/ml. | |
| BCN5718 | Aristolactam BIII |
| 1. Aristolactam BIII has moderate antitumor activity in selected cell lines. 2. Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, HT-29 and A549 cell lines in vitro. | |
| BCN5732 | 2-Oxopomolic acid |
| 1. 2-Oxopomolic acid shows cytotoxic activity. 2. 2-Oxopomolic acid shows radical-scavenging activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E). 3. 2-Oxopomolic acid shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. | |
| BCN5743 | Myriceric acid B |
| 1. Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. 2. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 value of 6.8 uM, it also exhibits cytotoxic activity towards the MOLT-3 cell line with IC50 values of 3.9 uM. | |
