Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5431 | Totaradiol |
| 1. Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. 2. Totaradiol exhibits cytotoxic activity against the A2780 ovarian cancer cell line. | |
| BCN5443 | Gelsevirine |
| 1. Gelsevirine has anxiolytic activity, may be via the agonist action of glycine receptor in the brain. 2. Gelsevirine can significantly inhibit the proliferation of human carcinoma cell line SW480 and MGC80-3 in a dose-dependent manner, the 50% inhibiting concentration(IC50)of gelsevirine on SW480 cells and MGC80-3 cells are 1.41±0.06 mM and 1.22±0.11 mM respectively. | |
| BCN5449 | Kamebanin |
| 1. Kamebanin, a natural diterpenoid, has antibacterial activity. 2. Kamebanin shows efficient cytotoxic activity against HeLa and HL-60 cells. | |
| BCN5451 | Epitulipinolide diepoxide |
| 1. Epitulipinolide diepoxide has antioxidative and chemopreventive activities in skin melanoma cells, can significantly inhibit the proliferation of melanoma cells. 2. Epitulipinolide diepoxide possessea cytotoxic activity against KB cells. | |
| BCN5466 | Hirsutanonol |
| 1. Hirsutanonol or oregonin as an active ingredient composition for treating atopic dermatitis. 2. Hirsutanonol shows significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells. 3. Hirsutanonol has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. 4. Hirsutanonol shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells. 5. Hirsutanonol has chemoprotective effect on human lymphocytes DNA. 6. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies. | |
