Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6136 | 3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone |
| 1. 5,7,3',5'-Tetrahydroxy-6,4'-dimethoxyflavone exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity. 2. 5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. | |
| BCN6154 | Hyptadienic acid |
| 1. Hyptadienic acid exhibits moderate cytotoxicity against HepG2 cells. 2. Hyptadienic acid shows a marked anti-inflammatory effect, it also exhibits strong antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz(a)anthracene (DMBA) as an initiator and TPA as a promoter. | |
| BCN6158 | 2',4'-Dihydroxy-3',6'-dimethoxychalcone |
| 1. 2',4'-Dihydroxy-3',6'-dimethoxychalcone has cytotoxic activities against cancer cells. 2. 2',4'-Dihydroxy-3',6'-dimethoxychalcone has anti-inflammatory activity and anti-cholinesterase activity, it has significant NO inhibitory activity. | |
| BCN6168 | Pimpinellin |
| Pimpinellin has phototoxic, it acts as antagonist of proteins with GABA receptor activity. Pimpinellin has anti- inflammatory, and cytotoxic activities. Pimpinellin also has anti-bacterial activity, it shows inhibitory activity against Mycobacterium tuberculosis strain H37Ra , with MICs of 812 uM and IC50s of 389 uM. | |
| BCN6180 | Heudelotinone |
| 1. Heudelotinone shows cytotoxicity against three cancer cell lines A549, Hela, and SMMC-7721( IC50 values of 16.04, 10.67 and 21.68 uM , respectively). | |
