Products with Cytotoxic bioactivity

Cat.No. Product Name
BCN3074 Isomorellic acid
1. Isomorellic acid is a cytotoxic caged xanthone.
BCN3078 Isogambogic acid
1. Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines.
BCN3081 30-Hydroxygambogic acid
1. 30-Hydroxygambogic acid exhibits significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines.
BCN3106 9,10-Dimethoxycanthin-6-one
9,10-Dimethoxycanthin-6-one shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 5.0 microM).
BCN3108 Eurycomalactone
1. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)]. 2. Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. 3. Eurycomalactone displays antiplasmodial activity against Gombak A isolate.

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