Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2525 | Eupalinolide B |
| Eupalinolide B demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.Eupalinolide B and Eupalinolide A induce the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90, they could be beneficial for use in cosmetics and medicines as a consequence of their inhibitory action on UV-induced skin damage and melanin production. | |
| BCN2526 | Garcinone D |
| 1. Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml. 2. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM. 3. Garcinone D exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. | |
| BCN2530 | Khasianine |
| Khasianine exhibits strong activity against liver damage induced by CCl4. | |
| BCN2590 | Poncirin |
| Poncirin has anticancer, anti-bacterial and anti-inflammatory activities; it prevents adipogenesis, enhances osteoblast differentiation in mesenchymal stem cellsincreased bone mineral density, and improves trabecular microarchitecture likely reflect increases bone formation and decreases bone resorption in GIO mice. Poncirin inhibits iNOS, COX-2, TNF-alpha and IL-6 expression via the down-regulation of NF-kappaB binding activity. | |
| BCN2593 | Schisanlactone E |
| 1. Schisanlactone E may show moderate cytotoxic activity against the human tumor cell lines Bel-7402, BGC-823, MCF-7 and HL-60. | |
