Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1834 | Discodermide |
| 1. Discodermide has antifungal and cytotoxic activities. | |
| BCN1904 | Convolvine |
| 1. Convolvine and its derivatives exhibit pronounced antihypoxic, immunomodulating, and anti-inflammatory activity. 2. Convolvine blocks the M-receptors of the heart and intestine but raises the sensitivity of the M-receptors of the salivary gland and of the CNS,convolvine has revealed characteristics of a sedative and nootropic agent. 3. Convolvine and its derivatives exhibit cytotoxic activity, the alkaloids N-benzylconvolvine and N-chloroacetylconvolvine at concentrations of 10 ug/mL exhibit the greatest activity against HeLa and Hep cancer cell cultures. | |
| BCN2066 | Doronenine |
| 1. Doronenine shows moderate cytotoxicity on cancerous U-937 cells. | |
| BCN2297 | Bufarenogin |
| 1. ψ-Bufarenogin exhibits potent therapeutic effect in xenografted human hepatoma without notable side effects,at least partially,via inhibiting receptor tyrosine kinases-regulated signaling. 2. ψ-Bufarenogin has inhibitory activity on human kidney Na(+)/K(+)-ATPase. 3. ψ-Bufarenogin has cytotoxicity against HepG2 and MCF-7 human cancer cells. | |
| BCN2315 | Pristimerin |
| Pristimerin is a naturally occurring triterpenoid that has been shown to suppress the proliferation of various cancer cell lines at the concentration (IC50) range of 0.2-4 μM, including those of breast, glioma, prostate, pancreatic, ovarian, colon. Pristimerin exhibits inhibitory effects against diverse phytopathogenic fungi, it shows good preventive effect and curative effect against wheat powdery mildew in vivo. It has a wide spectrum of targets including ROS, IKK, NF-κB, Akt, mTOR, Bcr-Abl. | |
