Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2767 | Beta,beta-Dimethylacrylalkannin |
| Beta,beta-Dimethylacrylalkannin has radical scavenging activity, it exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 umol·L-1, it may be a new type of leading compounds for the treatment of diabetes. Beta,beta-Dimethylacrylalkannin has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value. Beta,beta-Dimethylacrylalkannin can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin. | |
| BCN2820 | Deacetyltaxol |
| 10-Deacetyltaxol and cephalomannine have cytotoxicity in human glial and neuroblastoma cell-lines, the tumors of the central and peripheral nervous system are sensitive to 10-deacetyltaxol and cephalomannine and these drugs are less toxic than taxol but remain within a therapeutic range. | |
| BCN2843 | Angeloylgomisin H |
| 1. Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines. 2. Angeloylgomisin H may present significant myocardial protective activity. | |
| BCN2879 | Dihydrodaidzin |
| 1. Dihydrodaidzin shows cytotoxic activities against human stomach carcinoma (Hs 740.T, Hs 756 T), breast adenocarcinoma (Hs 578 T, Hs 742.T), and prostate carcinoma (DU 145, LNCaP-FGC) cell lines. | |
| BCN2926 | Juncusol |
| 1. Juncusol shows significant activity against MRSA strains. 2. Juncusol can induce caspase-3-mediated cytotoxicity in HT22 cells. 3. Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg. | |
