Products with Cytotoxic bioactivity

Cat.No. Product Name
BCN2445 Ganoderenic acid D
Ganoderenic acid D is most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively.
BCN2479 7-Ethyl-10-Hydroxycamptothecin
7-Ethyl-10-hydroxycamptothecin shows cytotoxicity against breast cancer, it efficiently target-bind to the colon and lungs of mice.
BCN2512 12-O-Tiglylphorbol-13-isobutyrate
1. 12-O-Tetradecanoylphorbol-13-acetate has cytotoxic against in vitro P-388 lymphocytic leukemia and KB nasopharyngeal carcinoma cell.
BCN2521 Eupalinilide B
Eupalinilides B demonstrates potent cytotoxicity against P-388 and A-549 tumor cell lines.
BCN2524 Eupalinolide A
Eupalinolide A and Eupalinolide B induce the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90. They could be beneficial for use in cosmetics and medicines as a consequence of their inhibitory action on UV-induced skin damage and melanin production.

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