Products with Cytotoxic bioactivity

Cat.No. Product Name
BCN1437 3-O-(2'E ,4'E-decadienoyl)-20-O-acetylingenol
1. 3-O-(2′E,4′E-decadienoyl)-20-O-acetylingenol has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships.
BCN1441 14-Deoxy-11,12-didehydroandrographolide
14-Deoxy-11,12-didehydroandrographolide has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions, it causes negative chronotropic action and antagonised isoproterenol-induced positive chronotropic actions in a non-competitive and dose-dependent manner. 14-Deoxy-11,12-didehydroandrographolide can effectively ameliorate astrocytic pro-inflammatory reactions and prevent PC12 cell death with different efficacies, it may be candidates for treatment of spinal-cord injury and neurodegeneration.
BCN1492 7-Hydroxy-beta-carboline-1-propionic acid
1. 7-Hydroxy-beta-carboline-1-propionic acid shows cytotoxic activity.
BCN1494 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one
1. 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one shows moderate cytotoxicity against a human lung carcinoma cell line.
BCN1535 9-O-Feruloyl-5,5'-dimethoxylariciresinol
1. (+)-9'-O-trans-Feruloyl-5,5'-dimethoxylariciresinol shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approximately 12.68 microg/ml. 2. (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol can inhibit release of histamine from mast cells, it may have anti-allergic inflammatory effect.

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