Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2625 | 4'-Demethylpodophyllotoxin |
| 4'-Demethylpodophyllotoxin exhibits the remarkable cytotoxic potential in diverse cancer cell lines. | |
| BCN2653 | Phillygenin |
| Phillyrin, (+)-Phillygenin, and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(50) values. | |
| BCN2665 | Acetylshikonin |
| Acetylshikonin has anti-cancer and anti-inflammatory activity, it is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors. Certain shikonin derivatives(such as Acetylshikonin) act as modulators of the Nur77-mediated apoptotic pathway. | |
| BCN2667 | Baldrinal |
| 1. Baldrinal shows selective cytotoxicity against metastatic prostate cancer (PC-3M) and colon cancer (HCT-8) cell lines. 2. Baldrinal, valtrate, and acevaltrate are the quality control compounds of Valeriana jatamansi Jones. | |
| BCN2670 | Corytuberine |
| 1. Corytuberine was inhibited only by naloxone and that of bulbocapnine preferentially by yohimbine. | |
