Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1721 | Kaempferol tetraacetate |
| 1. Kaempferol tetraacetate exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1. 2. Kaempferol tetraacetate is a potent antiplatelet agent. | |
| BCN1808 | Lavendustin A |
| 1. Lavendustin A and hormothamnione exhibit cytotoxic effects on tumor cell lines. 2. Lavendustin A is a potent tyrosine kinase inhibitor of the epidermal growth factor (EGF) receptor, and an angiogenesis inhibitor. 3. Lavendustin A is a hyperbolic mixed-type inhibitor with respect to both ATP and the peptide substrate, with a major effect on the binding affinities for both substrates. 4. Lavendustin A at 0.1 nM-1 microM causes a concave-shaped inhibition of the insulin release stimulated by 7 mM glucose, the inhibitory effect can be overcomed by higher concentrations of glucose. | |
| BCN1821 | Aburatubolactam A |
| 1. Aburatubolactam A is an inhibitor of superoxide anion generation. 2. Aburatubolactam A has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging. | |
| BCN1832 | Cylindramide |
| 1. Cylindramide,a cytotoxic tetramic acid lactam isolated from the marine sponge Halichondria cylindrata, it is cytotoxic against B16 melanoma cells with an IC50 of 0.8 ug/mL. 2. Cylindramide shows promising antiproliferative activity against several tumour cell lines. 3. (+)-Cylindramide has anti-microbial properties. | |
