Products with Cytotoxic bioactivity

Cat.No. Product Name
BCN1358 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone
1. 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.
BCN1381 3-O-Acetyl-11-keto-beta-boswellic acid
3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(50) of 1.5 m muM.
BCN1382 3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol
1. 3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol, one toxic terpenoid from raw Gansui. 2. 3-O-(2′E,4′Z-decadienoyl)-20-O-acetylingenol has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships. 3. 3-O-(2′E,4′Z-decadienoyl)-20-O-acetyl-ingenol and 3-O-(2′E,4′E-decadienoyl)-ingenol show cytotoxicity on Namalwa cells with IC 50 values of 7.6 and 5.2 umol·L-1, respectively.
BCN1388 1,5-Bis(4-hydroxy-3-methoxyphenyl)penta-1,4-diene
1.1,5-Bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one has cytotoxic activities and tumour-selectivities. 2.1,5-Bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one has hypoglycemic activity.
BCN1415 9,9'-Di-O-(E)-feruloylsecoisolariciresinol
1. (+)-9,9′-O-Diferuloylsecoisolariciresinol has significant cytotoxic activity against the DU145, LNCaP, and A549 cell lines. 2. 1,4-O-Diferuloylsecoisolariciresinol(9,9'-Di-O-(E)-feruloylsecoisolariciresinol),and pierreione B, two novel inhibitors of mTOR signaling, have strong anticancer activity.

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